Li Ziyao, Li Jiahang, Li Boyang, Sun Yingying, Wang Changcheng
Department of General Surgery, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Front Oncol. 2025 Jul 15;15:1581949. doi: 10.3389/fonc.2025.1581949. eCollection 2025.
Primary duodenal adenocarcinoma (PDA) is rare and highly invasive malignancies. The onset of the disease is insidious. Patients are often diagnosed when digestive obstruction occurred, leading to poor nutritional status and reduced tolerance for surgical trauma. Additionally, patients commonly experience fluid depletion and gastric drying, which is recognized as a pattern of gastric dryness and fluid injury. This article presents a successful case treated with the modified Decoction for Regulating the Stomach and Resolving Phlegm Formula combined with partial duodenectomy, summarizes both Chinese and Western medical diagnostic and treatment strategies for this disease, and provides valuable clinical experience in treating it.
原发性十二指肠腺癌（PDA）是一种罕见且侵袭性很强的恶性肿瘤。该病起病隐匿。患者常在出现消化梗阻时才被诊断出来，导致营养状况不佳，对手术创伤的耐受性降低。此外，患者常出现津液耗伤和胃燥的情况，这被认为是胃燥津伤的一种表现。本文介绍了1例采用加味调胃化痰方联合部分十二指肠切除术治疗成功的病例，总结了中西医对该病的诊断和治疗策略，并提供了治疗该病的宝贵临床经验。
