Libzon Stephanie, Kidron Debora, Erlik Uri, Krajden-Haratz Karina, Hausman-Kedem Moran, Ben Sira Liat
Pediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Medical Center, 6 Weizmann Street, Tel Aviv, 6423906, Israel.
Department of Physical Therapy, School of Health Professions, Gray Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Pediatr Radiol. 2025 Aug;55(9):1952-1956. doi: 10.1007/s00247-025-06353-9. Epub 2025 Jul 30.
Subpial hemorrhage is a rare intracranial hemorrhage typically described in neonates. We report the first prenatal diagnosis of subpial hemorrhage in a 28-year-old primigravida, defined on fetal magnetic resonance imaging (MRI) by its hallmark cortical inward depression ("cortical buckling") and restricted diffusion on the apparent diffusion coefficient map, and later confirmed by autopsy. This case implicates intrinsic fetal factors-rather than birth trauma or neonatal asphyxia-in subpial hemorrhage pathogenesis and highlights the critical role of fetal MRI in distinguishing subpial hemorrhage from other fetal hemorrhages, with important implications for prenatal counseling and perinatal management.
软脑膜下出血是一种罕见的颅内出血，通常在新生儿中描述。我们报告了一例28岁初产妇软脑膜下出血的产前诊断，胎儿磁共振成像（MRI）通过其标志性的皮质向内凹陷（“皮质褶皱”）和表观扩散系数图上的扩散受限来定义，后来经尸检证实。该病例表明，软脑膜下出血的发病机制与胎儿内在因素有关，而非出生创伤或新生儿窒息，并突出了胎儿MRI在区分软脑膜下出血与其他胎儿出血方面的关键作用，这对产前咨询和围产期管理具有重要意义。
