Kim Jihyun, Seo Gitae, Im Chae Hyun, Jee Hye Mi, Lee Yong Ju, Kim Hyo-Bin, Lee Eun, Suh Dong In, Jeon You Hoon, Lee So-Yeon, Yang Hyeon-Jong, Lee Kee-Jae, Kim Woo Kyung, Ahn Kangmo
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Seoul, Korea.
Allergy Asthma Immunol Res. 2025 Jul;17(4):505-518. doi: 10.4168/aair.2025.17.4.505.
We aimed to investigate the prevalence of atopic dermatitis (AD) and its associated risk factors in Korean children in 2022, and to compare to our findings with previous results to identify changes or trends over time.
A nationwide, cross-sectional study of randomly selected schoolchildren aged 6-7, 9-10, and 12-13 years, respectively, was completed. Information was obtained through the International Study of Asthma and Allergies in Childhood questionnaire, and comparisons between the current and prior surveys performed in 1995, 2000, and 2010 were conducted using a trend test.
In the 2022 survey, the prevalence of "itchy eczema, ever" was 18.3% in 6- to 7-year-olds, 21.6% in 9- to 10-year-olds, and 18.8% in 12- to 13-year-olds. The prevalence of "AD diagnosis, ever" in 6- to 7-year-olds rose from 20.9% in 1995 to 35.4% in 2010, then dropped to 13.6% in 2022 ( < 0.001), while in 12- to 13-year-olds, it increased from 7.1% in 1995 to 23.7% in 2010, then declined to 17.5% in 2022 ( < 0.001). In 6- to 7-year-olds, the prevalence of "AD only" and "AD and asthma" decreased between 1995 and 2022 (all < 0.001). In 12- to 13-year-olds, the prevalence of "AD only," "AD and rhinitis," and "AD and asthma and rhinitis" all increased during the same period (all < 0.001).
The prevalence of AD decreased in Korean children aged 6-7 years and increased in those aged 12-13 years, respectively, between 1995 and 2022, with a concomitant rise in allergic comorbidities among adolescents, suggesting age-dependent trends influenced by diverse AD phenotypes.
我们旨在调查2022年韩国儿童特应性皮炎（AD）的患病率及其相关危险因素，并将我们的研究结果与之前的结果进行比较，以确定随时间的变化或趋势。
分别对6至7岁、9至10岁和12至13岁的随机选取学童进行了一项全国性横断面研究。通过儿童哮喘和过敏国际研究问卷获取信息，并使用趋势检验对1995年、2000年和2010年进行的当前调查与先前调查进行比较。
在2022年的调查中，6至7岁儿童中“曾患瘙痒性湿疹”的患病率为18.3%，9至10岁儿童中为21.6%，12至13岁儿童中为18.8%。6至7岁儿童中“曾被诊断为AD”的患病率从1995年的20.9%上升至2010年的35.4%，然后在2022年降至13.6%（<0.001），而在12至13岁儿童中，该患病率从1995年的7.1%上升至2010年的23.7%，然后在2022年降至17.5%（<0.001）。在6至7岁儿童中，1995年至2022年期间“仅患AD”和“患AD和哮喘”的患病率下降（均<0.001）。在12至13岁儿童中，同期“仅患AD”、“患AD和鼻炎”以及“患AD、哮喘和鼻炎”的患病率均有所上升（均<0.001）。
1995年至2022年期间，韩国6至7岁儿童AD患病率下降，12至13岁儿童AD患病率上升，同时青少年中过敏性合并症有所增加，提示受多种AD表型影响的年龄依赖性趋势。
