Döring Katja, Satyavolu Syam, Durisin Martin, Götz Friedrich, Lanfermann Heinrich, Warnecke Athanasia, Giesemann Anja
Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.
Department of Otolarnygology, Hannover Medical School, Hannover, Germany.
Rofo. 2025 Jul 30. doi: 10.1055/a-2659-8853.
To assess the long-term progression of otosclerosis lesions on temporal bone CT, particularly with regard to lesion expansion, distribution, and changes in density.This retrospective study analyzed all patients who underwent HRCT or CBCT for the diagnosis of otosclerosis between 2012 and 2022. The study population was screened for the presence of follow-up imaging. Patients with available imaging over a period of five years were included in the study. Demographic data, clinical symptoms, and imaging findings were analyzed using descriptive statistics. The imaging findings were grouped according to otosclerosis subtype (fenestral, retrofenestral, or internal auditory canal (IAC)) and the long-term course of otosclerosis was assessed in terms of density and size.35 patients were included in a follow-up study with an average duration of 100 months (range: 62-168 months, 5 to 14 years ) for otosclerosis. A total of 65 ears were affected. The patients were on average 48 ± 12.1 (range: 11-74) years old. Women (n= 24, 69%) were more than twice as likely to be affected as men (n= 11, 31%). Retrofenestral otosclerosis was the most common form (54%), followed by fenestral otosclerosis (40%). Otosclerosis around the IAC was significantly less common, accounting for just 6% of cases. In both fenestral and retrofenestral otosclerosis, an increase in otosclerotic volume between the initial and last follow-up imaging scans was observed in fewer than a third of cases (16% vs. 20.6%; Table 2). The density increased in some cases over time, affecting 24% of fenestral and 38.2% of retrofenestral cases. If the IAC was affected, imaging showed no changes in extent or density over time.Over the long term (five to 14 years), slight changes in density (increasing sclerosis) and size expansion can only be observed in approximately one third of patients. A progression from fenetral to retrofenestral otosclerosis was not documented in any of the cases. · There are no significant changes in density and volume increase in the long-term course of otosclerosis.. · Progression from fenestral to retrofenestral otosclerosis was not observed in any case.. · The slight morphological progression of CT lesions observed in individual cases in our study is consistent with the limited progression of hearing loss observed in two-thirds of the remaining patients in Ishai et al.'s study.. · Döring K, Satyavolu S, Durisin M et al. Long-term evaluation of otosclerosis on temporal bone CT. Rofo 2025; DOI 10.1055/a-2659-8853.
为评估颞骨CT上耳硬化病变的长期进展情况，尤其是病变的扩展、分布及密度变化。本回顾性研究分析了2012年至2022年间因诊断耳硬化而接受高分辨率CT（HRCT）或锥形束CT（CBCT）检查的所有患者。对研究人群进行筛查以确定是否存在随访影像资料。纳入在五年期间有可用影像资料的患者。使用描述性统计分析人口统计学数据、临床症状及影像表现。根据耳硬化亚型（窗前型、窗后型或内耳道（IAC）型）对影像表现进行分组，并从密度和大小方面评估耳硬化的长期病程。35例患者纳入耳硬化随访研究，平均随访时长为100个月（范围：62 - 168个月，5至14年）。共有65只耳朵受累。患者平均年龄为48±12.1岁（范围：11 - 74岁）。女性（n = 24，69%）受累可能性是男性（n = 11，31%）的两倍多。窗后型耳硬化是最常见的类型（54%），其次是窗前型耳硬化（40%）。IAC周围的耳硬化明显较少见，仅占病例的6%。在窗前型和窗后型耳硬化中，不到三分之一的病例在首次和末次随访影像扫描之间观察到耳硬化体积增加（分别为16%和20.6%；表2）。部分病例密度随时间增加，窗前型病例中24%、窗后型病例中38.2%出现这种情况。若IAC受累，影像显示随时间范围和密度均无变化。从长期（5至14年）来看，仅约三分之一的患者可观察到密度有轻微变化（硬化增加）和大小扩展。未记录到任何一例从窗前型耳硬化进展为窗后型耳硬化的情况。·耳硬化的长期病程中密度和体积增加无显著变化。·未观察到任何一例从窗前型耳硬化进展为窗后型耳硬化的情况。·我们研究中个别病例观察到的CT病变轻微形态学进展与Ishai等人研究中其余三分之二患者观察到的听力损失有限进展一致。·Döring K, Satyavolu S, Durisin M等。颞骨CT对耳硬化的长期评估。Rofo 2025；DOI 10.1055/a - 2659 - 8853。
