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Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding.

作者信息

Jenkins Kathy J

机构信息

Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

JACC Basic Transl Sci. 2025 Jul;10(7):101296. doi: 10.1016/j.jacbts.2025.04.010.

DOI:10.1016/j.jacbts.2025.04.010
PMID:40738514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12434199/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea73/12434199/79c001475633/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea73/12434199/79c001475633/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea73/12434199/79c001475633/ga1.jpg

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本文引用的文献

1
Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model.使用新生大鼠模型评估西罗莫司对小儿肺静脉狭窄的治疗效果
JACC Basic Transl Sci. 2025 Jul;10(7):101229. doi: 10.1016/j.jacbts.2025.01.010. Epub 2025 Apr 2.
2
Systemic Sirolimus Therapy Is Associated With Reduced Intervention Frequency in Pulmonary Vein Stenosis.全身西罗莫司治疗与肺静脉狭窄干预频率降低相关。
JACC Adv. 2024 Nov 15;3(12):101401. doi: 10.1016/j.jacadv.2024.101401. eCollection 2024 Dec.
3
The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis: Evidence from Two Case Studies.
高壁面切应力在肺静脉狭窄进展中的作用：来自两个病例研究的证据。
Children (Basel). 2021 Aug 25;8(9):729. doi: 10.3390/children8090729.
4
Systemic Sirolimus Therapy for Infants and Children With Pulmonary Vein Stenosis.系统性西罗莫司治疗婴儿和儿童肺静脉狭窄。
J Am Coll Cardiol. 2021 Jun 8;77(22):2807-2818. doi: 10.1016/j.jacc.2021.04.013.
5
Progression of vascular remodeling in pulmonary vein obstruction.肺静脉阻塞中血管重构的进展。
J Thorac Cardiovasc Surg. 2020 Sep;160(3):777-790.e5. doi: 10.1016/j.jtcvs.2020.01.098. Epub 2020 Feb 26.
6
Adjunct Targeted Biologic Inhibition Agents to Treat Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis.针对侵袭性多血管腔内儿童肺静脉狭窄的辅助靶向生物抑制剂治疗。
J Pediatr. 2018 Jul;198:29-35.e5. doi: 10.1016/j.jpeds.2018.01.029. Epub 2018 Mar 23.
7
Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis.氯沙坦可改善猪肺静脉狭窄模型中的“上游”肺静脉血管病变。
J Thorac Cardiovasc Surg. 2014 Dec;148(6):2550-7. doi: 10.1016/j.jtcvs.2014.07.050. Epub 2014 Aug 1.
8
A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children.长春碱与甲氨蝶呤用于婴幼儿多支肺静脉腔内狭窄的前瞻性II期试验。
Congenit Heart Dis. 2011 Nov-Dec;6(6):608-23. doi: 10.1111/j.1747-0803.2011.00574.x. Epub 2011 Nov 11.
9
Pulmonary vein stenosis: expression of receptor tyrosine kinases by lesional cells.肺静脉狭窄：病变细胞中受体酪氨酸激酶的表达
Cardiovasc Pathol. 2006 Mar-Apr;15(2):91-9. doi: 10.1016/j.carpath.2005.11.006.
10
Mechanism of pulmonary vein stenosis in infants with normally connected veins.静脉连接正常的婴儿肺静脉狭窄的机制
Am J Cardiol. 2000 Sep 1;86(5):577-9, A10. doi: 10.1016/s0002-9149(00)01022-5.