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代谢组学在急性呼吸窘迫综合征中的应用:一项叙述性综述。

Application of metabolomics in acute respiratory distress syndrome: A narrative review.

作者信息

Song Xiu-Yan, Qin Hao, Zhang Wei

机构信息

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Second Military Medical University, Shanghai, China.

出版信息

Sci Prog. 2025 Jul-Sep;108(3):368504251356317. doi: 10.1177/00368504251356317. Epub 2025 Jul 30.

Abstract

Acute respiratory distress syndrome (ARDS) is a clinical condition characterized by damage and inflammation of the alveolar-capillary membrane, which is associated with high incidence and mortality rates. Metabolomics, a significant field of systematic biology, provides a novel perspective for understanding the pathophysiological mechanisms underlying ARDS by analyzing small molecule metabolites in biological samples. This narrative review explores the application of metabolomics in ARDS.

摘要

急性呼吸窘迫综合征(ARDS)是一种以肺泡-毛细血管膜损伤和炎症为特征的临床病症,其发病率和死亡率都很高。代谢组学作为系统生物学的一个重要领域,通过分析生物样本中的小分子代谢物,为理解ARDS潜在的病理生理机制提供了新的视角。这篇叙述性综述探讨了代谢组学在ARDS中的应用。

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