Suh Min Jung, Ahn Sohyun, Byun Ji Yeon
Ewha Womans University College of Medicine, Seoul, Korea.
Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea.
Ewha Med J. 2025 Jul;48(3):e44. doi: 10.12771/emj.2025.00486. Epub 2025 Jul 22.
This study developed and validated a deep learning model for the automated early detection of androgenetic alopecia (AGA) using trichoscopic images, and evaluated the model's diagnostic performance in a Korean clinical cohort.
We conducted a retrospective observational study using 318 trichoscopic scalp images labeled by board-certified dermatologists according to the Basic and Specific (BASP) system, collected at Ewha Womans University Medical Center between July 2018 and January 2024. The images were categorized as BASP 0 (no hair loss) or BASP 1-3 (early-stage hair loss). A ResNet-18 convolutional neural network, pretrained on ImageNet, was fine-tuned for binary classification. Internal validation was performed using stratified 5-fold cross-validation, and external validation was conducted through ensemble soft voting on a separate hold-out test set of 20 images. Model performance was measured by accuracy, precision, recall, F1-score, and area under the curve (AUC), with 95% confidence intervals (CIs) calculated for hold-out accuracy.
Internal validation revealed robust model performance, with 4 out of 5 folds achieving an accuracy above 0.90 and an AUC above 0.93. In external validation on the hold-out test set, the ensemble model achieved an accuracy of 0.90 (95% CI, 0.77-1.03) and an AUC of 0.97, with perfect recall for early-stage hair loss. No missing data were present, and the model demonstrated stable convergence without requiring data augmentation.
This model demonstrated high accuracy and generalizability for detecting early-stage AGA from trichoscopic images, supporting its potential utility as a screening tool in clinical and teledermatology settings.
本研究开发并验证了一种深度学习模型,用于使用毛囊镜图像自动早期检测雄激素性脱发(AGA),并评估该模型在韩国临床队列中的诊断性能。
我们进行了一项回顾性观察研究,使用了318张由皮肤科认证医生根据基本和特定(BASP)系统标记的头皮毛囊镜图像,这些图像于2018年7月至2024年1月在梨花女子大学医学中心收集。图像被分类为BASP 0(无脱发)或BASP 1 - 3(早期脱发)。在ImageNet上预训练的ResNet - 18卷积神经网络针对二分类进行了微调。内部验证使用分层5折交叉验证进行,外部验证通过对20张单独的保留测试集进行集成软投票来进行。模型性能通过准确率、精确率、召回率、F1分数和曲线下面积(AUC)来衡量,并计算保留准确率的95%置信区间(CI)。
内部验证显示模型性能稳健,5折中4折的准确率高于0.90,AUC高于0.93。在保留测试集的外部验证中,集成模型的准确率为0.90(95% CI,0.77 - 1.03),AUC为0.97,对早期脱发的召回率完美。不存在缺失数据,并且模型在无需数据增强的情况下展示了稳定的收敛。
该模型在从毛囊镜图像检测早期AGA方面表现出高准确率和泛化能力,支持其作为临床和远程皮肤病学环境中筛查工具的潜在效用。