Khatri Dhurba, Gahatraj Nand Ram, Chhetri Yamuna, Kc Bhakta Bahadur, Paudel Shishir
School of Health and Allied Sciences, Faculty of Health Sciences Pokhara University Kaski Nepal.
Kathmandu Institute of Child Health Hepali Height, Budhanilakantha Kathmandu Nepal.
Health Sci Rep. 2025 Jul 30;8(8):e71132. doi: 10.1002/hsr2.71132. eCollection 2025 Aug.
Kidney failure significantly impacts patients' quality of life (QoL), posing a public health concern due to its effects on well-being, satisfaction, and the increased demand for social and healthcare services. Understanding QoL determinants is critical for improving patient outcomes. Aim. This study assessed the QoL of kidney failure patients undergoing hemodialysis in Pokhara Metropolitan City, Nepal.
A cross-sectional study was conducted in 2017 among 132 kidney failure patients attending dialysis centers in Pokhara. Data were collected through face-to-face interviews and observations using the Short Form-36 (SF-36) Health Survey and a structured checklist. Descriptive statistics were used for frequency distribution, percentage, mean score, and standard deviation. Student's unpaired -test and ANOVA were used to compare the mean score differences of the quality of life among the groups.
The mean overall QoL score was 38.9 ± 6.21, with physical component summary (PCS) and mental component summary (MCS) scores of 36.55 ± 6.74 and 41.23 ± 13.36, respectively. While most participants (86.5%) were satisfied with personal relationships, 10.6% reported experiencing social discrimination or stigma, and 55% had not been invited to social events. Economic status and participation in social organizations were significantly associated with higher QoL scores across PCS, MCS, and overall QoL ( < 0.05).
The majority of patients suffering from kidney failure had overall poor quality of life. Social support and wealth index played a significant role in the quality of life. The findings suggest the need of enhancing social support systems and promoting vocational rehabilitation could improve QoL for this population.
肾衰竭严重影响患者的生活质量（QoL），因其对幸福感、满意度的影响以及对社会和医疗服务需求的增加，引发了公共卫生关注。了解生活质量的决定因素对于改善患者预后至关重要。目的：本研究评估了尼泊尔博卡拉市接受血液透析的肾衰竭患者的生活质量。
2017年对博卡拉透析中心的132名肾衰竭患者进行了横断面研究。通过使用简短健康调查问卷（SF-36）和结构化检查表进行面对面访谈和观察来收集数据。描述性统计用于频率分布、百分比、平均得分和标准差。采用学生独立样本t检验和方差分析来比较各组生活质量的平均得分差异。
总体生活质量平均得分为38.9±6.21，身体成分总结（PCS）得分和心理成分总结（MCS）得分分别为36.55±6.74和41.23±13.36。虽然大多数参与者（86.5%）对人际关系感到满意，但10.6%的人报告经历过社会歧视或耻辱，55%的人未被邀请参加社交活动。经济状况和参与社会组织与PCS、MCS及总体生活质量的较高得分显著相关（P<0.05）。
大多数肾衰竭患者的总体生活质量较差。社会支持和财富指数在生活质量中发挥了重要作用。研究结果表明，加强社会支持系统和促进职业康复可能会改善这一人群的生活质量。
