Quigg R J, Idelson B A, Yoburn D C, Hymes J L, Schick E C, Bernard D B
Arch Intern Med. 1985 Dec;145(12):2249-50.
Five patients receiving maintenance hemodialysis for end-stage renal disease underwent therapeutic pericardiocentesis for pericarditis manifested by either cardiac tamponade or effusion unresponsive to conservative therapy. Pericardiocentesis was followed by a one-time instillation of triamcinolone hexacetonide, a nonabsorbable corticosteroid, into the pericardial space with subsequent needle withdrawal. All patients had prompt hemodynamic and symptomatic improvement. Serial echocardiograms showed resolution of the pericardial effusion in all patients. Follow-up evaluation for six months to six years has shown no clinical or postmortem evidence of recurrence. This procedure appears safe and effective and potentially can obviate the need for prolonged catheter drainage or more invasive surgical procedures as therapy for these patients.
五名接受维持性血液透析治疗终末期肾病的患者因心包炎接受了治疗性心包穿刺术，心包炎表现为心脏压塞或对保守治疗无反应的积液。心包穿刺术后，将不可吸收的皮质类固醇曲安奈德六醋酸酯一次性注入心包腔，随后拔出针头。所有患者的血流动力学和症状均迅速改善。连续超声心动图显示所有患者的心包积液均已消退。六个月至六年的随访评估未发现复发的临床或尸检证据。该手术似乎安全有效，有可能避免对这些患者进行长期导管引流或更具侵入性的外科手术。
