Bergantin Leandro Bueno
Department of Pharmacology, Universidade Federal de São Paulo, São Paulo 04039-032, Brazil.
World J Psychiatry. 2025 Jul 19;15(7):107130. doi: 10.5498/wjp.v15.i7.107130.
Atrial fibrillation (AF) is a very common tachyarrhythmia in clinical practice. Several risk factors, such as higher inflammatory marker levels, diabetes mellitus, hypertension, valvular disease, ischemic heart disease, heart failure, and obesity have been proposed to enhance the risk of AF, contributing to higher healthcare system utilization rates and socioeconomic costs. Some interesting studies also investigated the link between AF and psychiatric diseases. This article debates this link between AF and psychiatric diseases from the perspective of Ca/cAMP signaling.
心房颤动（AF）是临床实践中非常常见的快速性心律失常。已提出多种风险因素，如较高的炎症标志物水平、糖尿病、高血压、瓣膜病、缺血性心脏病、心力衰竭和肥胖，会增加房颤风险，导致更高的医疗系统利用率和社会经济成本。一些有趣的研究还调查了房颤与精神疾病之间的联系。本文从钙/环磷酸腺苷（Ca/cAMP）信号传导的角度探讨房颤与精神疾病之间的这种联系。
