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[新生儿及1岁以内婴儿冠状动脉内膜类脂沉积症]

[Intimal lipoidosis of the coronary arteries of newborn infants and infants in the 1st year of life].

作者信息

Sultanaliev A A, Zhdanov V S

出版信息

Arkh Patol. 1985;47(10):36-42.

PMID:4074140
Abstract

Post-mortem morphological examination of the coronary arteries in 76 newborns and children of the first year of life was performed. Cases of the cardio-vascular pathology were not included into the study. Intimal thickening, either diffuse or focal, was revealed in 58 cases. The degree and frequency of the diffuse thickening of the intima (DTI) were higher in boys. DTI was present predominantly in the anterior interventricular artery and much less frequently in the circumflexal coronary artery. Intimal lipoidosis was found un 21 cases, with the same incidence in both boys and girls, but somewhat more frequently in the right coronary artery. Topography of both intimal lipoidosis and DTI was similar. The traces of cholesterol, its esters and predominantly neutral fat were defected histochemically in the foci of intimal lipoidosis.

摘要

对76例新生儿及1岁儿童的冠状动脉进行了尸检形态学检查。心血管病理病例未纳入本研究。58例发现有内膜增厚,呈弥漫性或局灶性。男孩内膜弥漫性增厚(DTI)的程度和频率更高。DTI主要出现在前室间动脉,而在旋支冠状动脉中出现的频率要低得多。21例发现有内膜类脂沉积,男孩和女孩的发生率相同,但在右冠状动脉中出现的频率略高。内膜类脂沉积和DTI的分布情况相似。在内膜类脂沉积灶中,通过组织化学方法检测到了胆固醇、其酯类,主要是中性脂肪的痕迹。

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