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心力衰竭患者症状网络同步分析:一项横断面研究。

Simultaneous Symptom Network Analysis of Heart Failure Patients: A Cross-Sectional Study.

作者信息

Wu Rui, Chen Lu, Li Yingjie, Wang Huiwen, Liu Mengdie, Yao Yingxia, Chen Huiyan, Xiao Dan

机构信息

Department of Cardiology, The Second Affiliated Hospital of Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.

School of Nursing, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.

出版信息

Risk Manag Healthc Policy. 2025 Jul 26;18:2493-2503. doi: 10.2147/RMHP.S520974. eCollection 2025.

Abstract

CONTEXT

Heart failure is a complex clinical syndrome associated with various symptoms that significantly impact patients' quality of life. Effective management of these symptoms remains a major challenge. Identifying and understanding the interactions between these symptoms is crucial for improving symptom control and patient outcomes.

OBJECTIVE

This study aimed to investigate the incidence and severity of symptoms in heart failure patients, construct a symptom network of heart failure patients, and explore the centrality of symptoms in the network. The goal was to identify core symptoms and explore the potential targets for symptom intervention.

METHODS

A total of 1051 heart failure patients were selected through convenience sampling. The Chinese version of the Memorial Heart Failure Symptom Assessment Scale was used to assess the prevalence and severity of symptoms. Regularized partial correlation network analysis was employed to construct the symptom network and evaluate the centrality of each symptom within the network.

RESULTS

Palpitations were found to be the most common symptom among heart failure patients, while lack of energy and depression were the most severe symptoms. In the symptom network, chest pain emerged as the core symptom with the highest predictability.

CONCLUSION

Intervening with chest pain as the core symptom can effectively reduce the severity of the entire symptom network. Early intervention for symptoms such as lack of energy can alleviate the burden of symptom management. Identifying predictable symptoms can help guide targeted symptom management strategies. Healthcare professionals can use the symptom patterns identified in this study to develop more precise and effective symptom management plans for heart failure patients.

摘要

背景

心力衰竭是一种复杂的临床综合征,伴有多种症状,严重影响患者的生活质量。有效管理这些症状仍然是一项重大挑战。识别和理解这些症状之间的相互作用对于改善症状控制和患者预后至关重要。

目的

本研究旨在调查心力衰竭患者症状的发生率和严重程度,构建心力衰竭患者的症状网络,并探索网络中症状的中心性。目标是识别核心症状并探索症状干预的潜在靶点。

方法

通过便利抽样选取了1051例心力衰竭患者。使用中文版的纪念心力衰竭症状评估量表评估症状的发生率和严重程度。采用正则化偏相关网络分析构建症状网络并评估每个症状在网络中的中心性。

结果

心悸被发现是心力衰竭患者中最常见的症状,而精力不足和抑郁是最严重的症状。在症状网络中,胸痛成为预测性最高的核心症状。

结论

以胸痛为核心症状进行干预可有效降低整个症状网络的严重程度。对精力不足等症状进行早期干预可减轻症状管理的负担。识别可预测的症状有助于指导有针对性的症状管理策略。医疗保健专业人员可利用本研究中确定的症状模式为心力衰竭患者制定更精确有效的症状管理计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8efc/12309574/9f647209313b/RMHP-18-2493-g0001.jpg

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