Scaioli Giacomo, Varì Maria Grazia, Barbera Giulia, Durbano Alessandro, Pinto Sonia, Lo Moro Giuseppina, Bert Fabrizio, Siliquini Roberta
Department of Public Health Sciences and Pediatrics, University of Turin.
Local Health Authority, A.S.L. TO3.
Eur J Cancer Prev. 2025 Jul 23. doi: 10.1097/CEJ.0000000000000985.
This systematic review focuses on the screening invitation process to identify the most effective methods for increasing participation in oncological cancer screening programs. The success of cancer screening programs heavily relies on the invitation process within a structured framework. This PRISMA-P compliant systematic review focuses on randomized controlled trials conducted worldwide between 2010 and 2021, with participation rates as the primary outcome. From the 7790 initially retrieved articles, 29 underwent quality assessment using the Cochrane Collaboration tool. The analysis revealed 13 studies with low risk, 11 with medium risk, and five with high risk of bias; the latter were excluded from further analysis. The review examined intervention types, control types, analysis approaches, and the effectiveness of various invitation methods. Different communication means, such as letters, text messages, phone calls, and face-to-face consultations, were evaluated along with the roles of various professionals. Specific invitation methods significantly increased participation rates, with multistep approaches using multiple communication channels proving more effective. Advanced notification techniques, interactive approaches such as phone calls and counseling sessions, and mailing fecal immunochemical test or fecal occult blood test kits directly with invitation letters demonstrated increased participation rates. In contrast, engaging general practitioners, attaching supplementary materials to invitation letters, sending reminders after the initial invitation, and applying behavioral theories showed limited impact on participation rates. The findings emphasize the importance of tailored, multistep invitation strategies incorporating various communication channels for optimal success in cancer screening programs.
本系统评价聚焦于筛查邀请流程,以确定提高肿瘤癌症筛查项目参与率的最有效方法。癌症筛查项目的成功在很大程度上依赖于结构化框架内的邀请流程。这项符合PRISMA-P标准的系统评价聚焦于2010年至2021年期间在全球范围内开展的随机对照试验,将参与率作为主要结果。从最初检索到的7790篇文章中,有29篇使用Cochrane协作工具进行了质量评估。分析显示,13项研究风险较低,11项研究风险中等,5项研究存在高偏倚风险;后5项研究被排除在进一步分析之外。该评价考察了干预类型、对照类型、分析方法以及各种邀请方法的有效性。对不同的沟通方式,如信件、短信、电话和面对面咨询,以及各类专业人员的作用进行了评估。特定的邀请方法显著提高了参与率,使用多种沟通渠道的多步骤方法被证明更有效。提前通知技术、电话和咨询会议等互动方式,以及随邀请函直接邮寄粪便免疫化学检测或粪便潜血检测试剂盒,都显示出参与率有所提高。相比之下,让全科医生参与、在邀请函中附上补充材料、在初次邀请后发送提醒以及应用行为理论,对参与率的影响有限。研究结果强调了采用量身定制的多步骤邀请策略并结合各种沟通渠道对于癌症筛查项目取得最佳成效的重要性。