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本文引用的文献

1
Podocyte NPRC Deficiency Attenuates Glomerular Fibrosis in Diabetic Mice.足细胞NPRC缺乏减轻糖尿病小鼠的肾小球纤维化
Circ Res. 2025 Jun 25. doi: 10.1161/CIRCRESAHA.124.325702.
2
Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis.利钠肽清除受体的足细胞特异性敲除对局灶节段性肾小球硬化具有足细胞保护作用。
PLoS One. 2025 Mar 10;20(3):e0319424. doi: 10.1371/journal.pone.0319424. eCollection 2025.
3
Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes.实时成像 cGMP 信号显示肾小球内皮细胞和足细胞之间存在显著差异。
Sci Rep. 2024 Oct 30;14(1):26099. doi: 10.1038/s41598-024-76768-1.
4
Estimated Lifetime Cardiovascular, Kidney, and Mortality Benefits of Combination Treatment With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Nonsteroidal MRA Compared With Conventional Care in Patients With Type 2 Diabetes and Albuminuria.估计 2 型糖尿病合并白蛋白尿患者接受 SGLT2 抑制剂、GLP-1 受体激动剂和非甾体类 MRA 联合治疗与常规治疗相比的终生心血管、肾脏和死亡率获益。
Circulation. 2024 Feb 6;149(6):450-462. doi: 10.1161/CIRCULATIONAHA.123.067584. Epub 2023 Nov 12.
5
Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association.心血管-肾脏-代谢健康：美国心脏协会的总统顾问报告
Circulation. 2023 Nov 14;148(20):1606-1635. doi: 10.1161/CIR.0000000000001184. Epub 2023 Oct 9.
6
NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice.NPRC 缺失通过抑制载脂蛋白 E 基因敲除小鼠的氧化应激、炎症和细胞凋亡来减轻动脉粥样硬化。
Signal Transduct Target Ther. 2023 Aug 9;8(1):290. doi: 10.1038/s41392-023-01560-y.
7
Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution.单细胞分辨率下可溶性鸟苷酸环化酶调节对糖尿病肾病的治疗效果。
Cell Rep Med. 2023 Apr 18;4(4):100992. doi: 10.1016/j.xcrm.2023.100992. Epub 2023 Apr 5.
8
Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys.利钠肽受体 A、B、C 在健康和患病小鼠肾脏中的定位。
Pflugers Arch. 2023 Mar;475(3):343-360. doi: 10.1007/s00424-022-02774-9. Epub 2022 Dec 8.
9
Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers.饮食依赖的脂肪组织利钠肽受体 C 表达受 PPARγ 通过长程远端增强子调控。
J Biol Chem. 2021 Aug;297(2):100941. doi: 10.1016/j.jbc.2021.100941. Epub 2021 Jul 7.
10
Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance.增强脂肪组织而非肌肉中的利钠肽信号传导可预防饮食诱导的肥胖和胰岛素抵抗。
Sci Signal. 2017 Jul 25;10(489):eaam6870. doi: 10.1126/scisignal.aam6870.

Salvaged Signals, Scarred Filters: Podocyte NPRC in Diabetic Kidney Disease.

作者信息

Cervantes Jocelyn, Kanter Jenny E

机构信息

Division of Metabolism, Endocrinology, and Nutrition, University of Washington Medicine Diabetes Institute, University of Washington, Seattle.

出版信息

Circ Res. 2025 Aug;137(4):548-550. doi: 10.1161/CIRCRESAHA.125.326944. Epub 2025 Jul 31.

DOI:10.1161/CIRCRESAHA.125.326944
PMID:40743306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12321215/
Abstract
摘要