肝脏组氨酸酶活性性别差异的内分泌调节
Endocrine regulation of sex differences in hepatic histidase activity.
作者信息
Lamartiniere C A
出版信息
Biochem J. 1985 Nov 1;231(3):785-7. doi: 10.1042/bj2310785.
Abstract
Hepatic histidase activity in adult female rats is twice that in adult male rats. Hypophysectomy and thyroidectomy result in a significant increase in hepatic histidase activities in males, but not in females. This effect on histidase is reversed by the exogenous administration of tri-iodothyronine, but not by ectopic pituitary glands or purified pituitary hormones.
摘要
成年雌性大鼠肝脏中的组氨酸酶活性是成年雄性大鼠的两倍。垂体切除和甲状腺切除会导致雄性大鼠肝脏组氨酸酶活性显著增加，但雌性大鼠不会。三碘甲状腺原氨酸的外源给药可逆转对组氨酸酶的这种影响，但异位垂体或纯化的垂体激素则不能。
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