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客观改善,主观不确定性:手术结果及患者报告结果测量信息系统(PROMIS)在重度近端指间关节挛缩中的作用

Objective Improvements, Subjective Uncertainty: Surgical Outcomes and the Role of PROMIS in Severe PIP Contractures.

作者信息

Sanchez-Navarro Gerardo E, Spindler Archie, Comunale Victoria, Linton Nadia, Jacobi Sophia, Hacquebord Jacques H

机构信息

NYU Langone Health, New York, NY, USA.

Universidad Central del Caribe School of Medicine, Bayamón, Puerto Rico.

出版信息

Hand (N Y). 2025 Jul 31:15589447251357043. doi: 10.1177/15589447251357043.

Abstract

BACKGROUND

Severe proximal interphalangeal (PIP) contractures in Dupuytren disease significantly impair hand function and quality of life. Surgical correction is common, but the relationship between improved joint mobility and patient-reported outcomes remains unclear. This study evaluated surgical outcomes for severe PIP contractures and assessed patient-reported function using Patient-Reported Outcomes Measurement Information System (PROMIS).

METHODS

A retrospective chart review included patients with severe PIP contractures treated surgically. Contractures were categorized by severity: group 1 (<29°), group 2 (30°-59°), group 3 (60°-89°), and group 4 (>90°). Objective outcomes were measured as contracture reduction at multiple time points (preoperative, immediate postoperative, and final follow-up) using a goniometer. The PROMIS scores for pain intensity, daily activity interference, and upper extremity function were collected preoperatively and at final follow-up. Statistical analyses included descriptive statistics, paired tests, and analysis of variance with post hoc Tukey tests ( < .05).

RESULTS

The study included 60 digits from 48 patients. Significant contracture reductions were observed across all groups, averaging more than 60%. However, PROMIS scores did not consistently reflect improvements in pain, activity interference, or upper extremity function. A significant decrease in upper extremity function was noted in group 3 (60°-89°). No operative complications or reoperations occurred.

CONCLUSIONS

Surgical correction markedly improves joint contracture but does not consistently enhance PROMIS-reported outcomes. These results question PROMIS applicability in this context and highlight the need for alternative assessment tools to better address functional recovery in patients with severe PIP contractures.

摘要

背景

杜普伊特伦挛缩症中严重的近端指间关节(PIP)挛缩会显著损害手部功能和生活质量。手术矫正很常见,但关节活动度改善与患者报告的结果之间的关系仍不清楚。本研究评估了严重PIP挛缩的手术结果,并使用患者报告结果测量信息系统(PROMIS)评估了患者报告的功能。

方法

一项回顾性图表审查纳入了接受手术治疗的严重PIP挛缩患者。挛缩按严重程度分类:1组(<29°),2组(30°-59°),3组(60°-89°),4组(>90°)。使用角度计在多个时间点(术前、术后即刻和最终随访)测量挛缩减少情况作为客观结果。术前和最终随访时收集疼痛强度、日常活动干扰和上肢功能的PROMIS评分。统计分析包括描述性统计、配对检验和事后Tukey检验的方差分析(P<.05)。

结果

该研究纳入了48例患者的60个手指。所有组均观察到挛缩显著减少,平均超过60%。然而,PROMIS评分并未始终反映出疼痛、活动干扰或上肢功能的改善。3组(60°-89°)的上肢功能显著下降。未发生手术并发症或再次手术。

结论

手术矫正显著改善关节挛缩,但并未始终提高PROMIS报告的结果。这些结果质疑了PROMIS在此背景下的适用性,并强调需要替代评估工具以更好地解决严重PIP挛缩患者的功能恢复问题。

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Pearls and pitfalls of PROMIS clinically significant outcomes in orthopaedic surgery.PROMIS 在矫形外科临床结局中的要点和陷阱。
Arch Orthop Trauma Surg. 2023 Nov;143(11):6617-6629. doi: 10.1007/s00402-023-04983-y. Epub 2023 Jul 12.
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Severity of contracture and self-reported disability in patients with Dupuytren's contracture referred for surgery.
J Hand Ther. 2011 Jan-Mar;24(1):6-10; quiz 11. doi: 10.1016/j.jht.2010.07.006. Epub 2010 Oct 16.
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A review of common practice in Dupuytren surgery.掌腱膜挛缩症手术常见操作综述。
Tech Hand Up Extrem Surg. 2005 Dec;9(4):178-87. doi: 10.1097/01.bth.0000186794.90431.a4.
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Functional benefit of Dupuytren's surgery.杜普伊特伦挛缩症手术的功能益处。
J Hand Surg Br. 2002 Aug;27(4):378-81. doi: 10.1054/jhsb.2002.0776.

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