Hegerty A S, Anderson R H, Ho S Y
Br Heart J. 1985 Dec;54(6):583-92. doi: 10.1136/hrt.54.6.583.
The hearts of 291 babies with congenital heart disease who died before the age of one were examined systematically by sequential segmental analysis to determine the lesions that were present. There was an abnormal connection between the cardiac segments in one third of cases. Patient ductus arteriosus, which is usually a common defect, was not an important finding at necropsy, whereas common arterial trunk (a rare defect) was found in 10%. The clinical and necropsy incidence of complete transposition was similar to that reported in earlier studies. The incidence of some lesions present at necropsy (for example Fallot's tetralogy) has altered over the past 10 years. A decline in the frequency with which a lesion is detected at necropsy may indicate advances in treatment or differences in classification. The presence of additional lesions influences the prognosis and subcategorisation within the major defect groupings gave some insight into the cause of death in many of the cases.
对291例1岁前死亡的先天性心脏病婴儿的心脏进行了系统的顺序节段分析，以确定存在的病变。三分之一的病例中存在心脏节段之间的异常连接。动脉导管未闭，这通常是一种常见缺陷，在尸检时并非重要发现，而共同动脉干（一种罕见缺陷）在10%的病例中被发现。完全性大动脉转位的临床和尸检发生率与早期研究报道的相似。过去10年中，一些尸检时存在的病变（如法洛四联症）的发生率发生了变化。尸检时检测到病变的频率下降可能表明治疗进展或分类差异。额外病变的存在会影响预后，主要缺陷分组中的子分类为许多病例的死亡原因提供了一些见解。
