Albeck H, Coleman M, Nielsen N H, Hansen H S, Hansen J P
Br J Cancer. 1985 Dec;52(6):909-14. doi: 10.1038/bjc.1985.276.
Evidence of epidemicity of nasopharyngeal carcinoma (NPC) was sought in Greenland Inuits, who have a high incidence of this cancer, by examining the births of NPC cases for evidence of clustering in time and space. Births of cases were concentrated in autumn and winter. Fifty-four cases were analysed, and a two-fold excess of clustering within one year was observed, both within single districts and between adjacent districts. This excess was not significant at the 5% level; about 90 cases would have been required to confirm the observed effect at this level of significance. It is suggested that a search for space-time clustering of NPC cases in larger high-risk populations might prove more fruitful.
通过检查鼻咽癌（NPC）病例的出生情况，以寻找时间和空间上的聚集证据，从而探寻格陵兰因纽特人中鼻咽癌的流行证据，该人群中这种癌症的发病率很高。病例的出生集中在秋季和冬季。对54例病例进行了分析，发现在单个地区内以及相邻地区之间，一年内聚集现象的发生率高出两倍。这种高出的发生率在5%的水平上并不显著；在这个显著性水平上，大约需要90例病例才能证实所观察到的效应。有人认为，在更大的高危人群中寻找鼻咽癌病例的时空聚集现象可能会更有成效。
