Increased risk of cancer in siblings of Alaskan native patients with nasopharyngeal carcinoma.
作者信息
Ireland B, Lanier A P, Knutson L, Clift S E, Harpster A
机构信息
Arctic Investigations Laboratory, Centers for Disease Control, Anchorage, Alaska 99501.
出版信息
Int J Epidemiol. 1988 Sep;17(3):509-11. doi: 10.1093/ije/17.3.509.
PMID:3209327
Abstract
Alaskan Natives (Eskimos, Indians, Aleuts) are at increased risk of developing nasopharyngeal cancer (NPC) and there is family clustering of NPC. This study reviewed the total cancer experience of relatives of NPC patients and found that siblings of Eskimo NPC patients had a nearly threefold risk. No cancer family syndrome was identified and the cancers diagnosed in the siblings were similar to those seen in the general Alaskan Eskimo population.
摘要
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