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冻结肩作为一种代谢信号:主张对非创伤性病例进行常规糖化血红蛋白筛查。

Frozen Shoulder as a Metabolic Signal: Advocating Routine HbA1c Screening in Atraumatic Cases.

作者信息

Swarnakar Raktim

机构信息

Physical Medicine and Rehabilitation, National Cancer Institute, Jhajjar Campus, All India Institute of Medical Sciences, New Delhi, IND.

出版信息

Cureus. 2025 Jun 29;17(6):e86999. doi: 10.7759/cureus.86999. eCollection 2025 Jun.

Abstract

Frozen shoulder, also known as adhesive capsulitis, is often regarded as a localized musculoskeletal disorder. However, it may also be an early indicator of underlying metabolic dysfunction, particularly diabetes or prediabetes. Many patients presenting with atraumatic, progressive shoulder stiffness are found to have elevated HbA1c levels despite normal fasting and postprandial glucose values. Diabetes-related tissue changes, such as collagen glycation and microvascular compromise, may contribute to the development of capsular fibrosis. Recognizing this, routine HbA1c screening in such presentations can aid early diagnosis of dysglycemia and enable timely intervention. This approach may promote interdisciplinary care and improve both systemic and shoulder outcomes. Clinicians should consider frozen shoulder within a broader metabolic-inflammatory framework, especially in middle-aged patients with persistent symptoms and no clear alternative diagnosis.

摘要

肩周炎,又称粘连性关节囊炎,通常被视为一种局部性肌肉骨骼疾病。然而,它也可能是潜在代谢功能障碍的早期指标,尤其是糖尿病或糖尿病前期。许多表现为非创伤性、进行性肩部僵硬的患者,尽管空腹和餐后血糖值正常,但糖化血红蛋白(HbA1c)水平却升高。糖尿病相关的组织变化,如胶原蛋白糖化和微血管损伤,可能导致关节囊纤维化的发展。认识到这一点,在此类病例中进行常规HbA1c筛查有助于早期诊断血糖异常并及时进行干预。这种方法可能促进多学科护理,并改善全身和肩部的治疗效果。临床医生应在更广泛的代谢 - 炎症框架内考虑肩周炎,尤其是在有持续症状且无明确替代诊断的中年患者中。

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