Banayan Hadasa, Liu Jieqi, Haoson Dominique
Internal Medicine, Jersey City Medical Center/RWJ Barnabas Health, Jersey City, USA.
Hematology and Oncology, Division of Blood Disorders, Rutgers Cancer Institute of New Jersey, New Brunswick, USA.
Cureus. 2025 Jul 1;17(7):e87133. doi: 10.7759/cureus.87133. eCollection 2025 Jul.
We present a case of hemophagocytic lymphohistiocytosis (HLH) with a complex presentation that could have been easily mistaken as one of many alternative diagnoses. Our patient, with chronic alcohol use disorder, presented with new-onset liver symptoms and pancytopenia. This case underscores the importance of clinical suspicion and further investigation of a wide differential. The purpose of this case report is to highlight the diagnostic challenges and nuances in patient presentation that can mislead healthcare providers while emphasizing the ambiguity of liver failure symptoms in patients with undiagnosed HLH.
我们报告一例噬血细胞性淋巴组织细胞增生症(HLH),其临床表现复杂,很容易被误诊为多种其他疾病之一。我们的患者患有慢性酒精使用障碍,出现了新发的肝脏症状和全血细胞减少。该病例强调了临床怀疑以及对广泛鉴别诊断进行进一步检查的重要性。本病例报告的目的是突出患者临床表现中可能误导医疗服务提供者的诊断挑战和细微差别,同时强调未确诊HLH患者肝衰竭症状的模糊性。