Zhang Yumeng, Chen Jiali, Liu Zhenmin, Zhang Shengyi, Wang Jiale, Shao Junhua, Yue Xiqing, Li Mohan
College of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
State Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Shanghai 200436, China.
Food Chem X. 2025 Jul 22;29:102798. doi: 10.1016/j.fochx.2025.102798. eCollection 2025 Jul.
Donkey colostrum (DC) is recognized as a valuable nutritional source; however, its extremely low lipid content (especially polar lipids) demands lipid supplementation during processing through the addition of fish oils, vegetable oils, or functional lipids. Therefore, a comprehensive characterization of polar lipids in both DC and bovine colostrum (BC) is required. In this study, totally 11 subclasses of 206 polar lipids in DC and BC were characterized. Using rigorous screening criteria (VIP > 1, < 0.05, and fold change >2 or < 0.5), 141 lipid species were identified as having significantly different polar lipids (SDPLs) between DC and BC. Subsequent investigations revealed six key lipid metabolic pathways, with the glycerophospholipid metabolism being the most critical. These findings substantially enhance our understanding of the polar lipid differences between DC and BC, while providing a theoretical basis for synergistic utilization of the two milk sources to optimize nutritional enrichment strategies.
驴初乳（DC）被认为是一种有价值的营养来源；然而，其极低的脂质含量（尤其是极性脂质）要求在加工过程中通过添加鱼油、植物油或功能性脂质来补充脂质。因此，需要对DC和牛初乳（BC）中的极性脂质进行全面表征。在本研究中，对DC和BC中206种极性脂质的11个亚类进行了表征。使用严格的筛选标准（VIP>1，<0.05，且倍数变化>2或<0.5），鉴定出141种脂质物种在DC和BC之间具有显著不同的极性脂质（SDPLs）。随后的研究揭示了六个关键的脂质代谢途径，其中甘油磷脂代谢最为关键。这些发现极大地增进了我们对DC和BC之间极性脂质差异的理解，同时为协同利用这两种乳源以优化营养强化策略提供了理论基础。
