BacNa Gene Therapy Improves Function of Infarcted Engineered Human Myocardium and NHPs.
作者信息
Wu Tianyu, Tee Nicole G Z, Siu Yiu Yan, Tornatore Anna, Bhattacharjee Abhishek, Koconis James, Loo Sze Jie, Su Liping, Li Binjie, Ye Lei, Bursac Nenad
机构信息
Department of Biomedical Engineering, Duke University, Durham, NC (T.W., Y.Y.S., A.T., A.B., J.K., B.L., N.B.).
National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore (N.G.Z.T., S.J.L., L.S., L.Y.).
出版信息
Circ Res. 2025 Aug 29;137(6):899-901. doi: 10.1161/CIRCRESAHA.125.326570. Epub 2025 Aug 1.
Abstract
摘要
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本文引用的文献
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Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.《心脏病与卒中统计数据-2023 更新：美国心脏协会报告》。
Circulation. 2023 Feb 21;147(8):e93-e621. doi: 10.1161/CIR.0000000000001123. Epub 2023 Jan 25.
2
Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy.用于心脏基因治疗的工程化细菌电压门控钠离子通道平台。
Nat Commun. 2022 Feb 2;13(1):620. doi: 10.1038/s41467-022-28251-6.
3
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues.心脏贴片平台可实现人类多能干细胞衍生的工程心脏组织的成熟和规模化。
Nat Commun. 2017 Nov 28;8(1):1825. doi: 10.1038/s41467-017-01946-x.
4
Direct comparison of efficiency and stability of gene transfer into the mammalian heart using adeno-associated virus versus adenovirus vectors.使用腺相关病毒与腺病毒载体将基因导入哺乳动物心脏的效率和稳定性的直接比较。
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