Novikov A N, Tkachenko S I, Stribul' T F, Ryndin V F
Biofizika. 1985 Nov-Dec;30(6):1042-5.
On the basis of the analysis of the described cooling regime of biological objects during low temperature preservation it is suggested that an optimal regime should have non-linear dependence of the rate of temperature change in time. By approximation of several experimental cooling regimes it is found that the exponential description of this process is the most correct. Advantages of using the exponential cooling regime instead of the linear ones during their optimization are grounded. The theoretical premises of the exponential cooling regime realization are described.
基于对低温保存期间生物物体所述冷却方式的分析,建议最佳方式应具有温度随时间变化率的非线性依赖关系。通过对几种实验冷却方式进行近似处理,发现对该过程采用指数描述最为合适。阐述了在优化过程中使用指数冷却方式而非线性冷却方式的优势。描述了实现指数冷却方式的理论前提。