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[应激状态下及预防性给予生育三烯酚后仓鼠的微循环系统]

[Microcirculatory system of hamsters under stress and following the prophylactic administration of ionol].

作者信息

Gorizontova M P

出版信息

Biull Eksp Biol Med. 1985 Dec;100(12):673-5.

PMID:4074866
Abstract

Biomicroscopic studies of hamster pouches have shown that 1-24-hour immobilization and 3-hour electrical stimulation induced terminal blood flow slowing, erythrocyte aggregation, plasmatization and vessel stasis. 24-hour immobilization and 3-hour electrical stimulation enhanced globulin permeability of venular microvessels. All types of extremal stimulation increased mast cell degranulation. Preventive antioxidant (ionol) administration normalized vascular permeability and suppressed mast cell degranulation in stress-exposed animals.

摘要

对仓鼠颊囊的生物显微镜研究表明,1 - 24小时固定和3小时电刺激会导致末梢血流减慢、红细胞聚集、血浆化和血管停滞。24小时固定和3小时电刺激会增强微静脉微血管的球蛋白通透性。所有类型的极端刺激都会增加肥大细胞脱颗粒。预防性给予抗氧化剂(ionol)可使应激暴露动物的血管通透性恢复正常,并抑制肥大细胞脱颗粒。

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Biull Eksp Biol Med. 1985 Dec;100(12):673-5.
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