Hutchison J B, Steimer T
Brain Res. 1985 Dec 23;360(1-2):366-9. doi: 10.1016/0006-8993(85)91256-9.
In vitro study of testosterone (T) metabolism shows that formation of 17 beta-oestradiol (E2) in the preoptic area is higher in male doves exposed to behavioural stimuli from interacting pairs than in visually isolated males or males that have interacted with females. Formation of 5 alpha-dihydrotestosterone, 5 beta-dihydrotestosterone and 5 beta-androstane-3 alpha, 17 beta-diol was similar in all groups, indicating that exposure to stimuli from interacting pairs influences aromatization of T and not other pathways of androgen metabolism. The results suggest that sexual stimuli, which do not involve tactile contact between male and female, affect local E2 formation in the brain.
睾酮(T)代谢的体外研究表明,与视觉隔离的雄性或与雌性有过互动的雄性相比,暴露于相互作用的配对行为刺激下的雄性鸽子视前区中17β-雌二醇(E2)的生成量更高。所有组中5α-双氢睾酮、5β-双氢睾酮和5β-雄甾烷-3α,17β-二醇的生成情况相似,这表明暴露于相互作用的配对刺激下会影响T的芳香化作用,而不会影响雄激素代谢的其他途径。结果表明,不涉及雌雄之间触觉接触的性刺激会影响大脑中局部E2的形成。