Wang Yuyin, Du Bang, Wu Guangxue
Civil Engineering, School of Engineering, College of Science and Engineering, University of Galway, Galway H91 TK33, Ireland.
Civil Engineering, School of Engineering, College of Science and Engineering, University of Galway, Galway H91 TK33, Ireland.
J Hazard Mater. 2025 Sep 15;496:139378. doi: 10.1016/j.jhazmat.2025.139378. Epub 2025 Jul 28.
Tetracycline enters the environment due to its incomplete absorption in humans and animals, posing a significant ecological threat. Tetracycline can hinder the biosystems when treating tetracycline-containing wastewater/waste through anaerobic digestion. This review summarizes the role of tetracycline in inhibiting system performance and related functional microorganisms in holistic process of anaerobic digestion. Tetracycline may primarily inhibit methanogenesis by suppressing acetogenesis, with methane production reductions ranging from 10 % to complete inhibition depending on factors such as tetracycline concentration, inoculum source, substrate composition, and temperature. As a refractory pollutant, tetracycline can be removed in anaerobic digestion systems through adsorption and biodegradation, with removal efficiencies reported between 14.8 % and over 90 %. This review systematically summarizes the mechanisms of tetracycline removal pathways and evaluates the potential contributions. Co-existence of readily biodegradable substrates, extended sludge retention time, and the regulation of environmental parameters such as pH and temperature are potential strategies to enhance tetracycline removal. Moreover, the addition of conductive materials has been identified as a promising strategy to serve as tetracycline adsorbents, facilitate direct interspecies electron transfer and mediate redox reactions, and act as microbial carriers to enhance microbial activity. Finally, this review highlights that the dynamic responses and microbial survival strategies under tetracycline stress deserve further investigation. A deeper understanding of these mechanisms will offer clear theoretical guidance for upgrading technologies for tetracycline-containing wastewater/waste treatment.
由于四环素在人和动物体内吸收不完全，其进入环境后会构成重大生态威胁。在处理含四环素的废水/废物时，四环素可通过厌氧消化阻碍生物系统。本综述总结了四环素在厌氧消化全过程中对系统性能及相关功能微生物的抑制作用。四环素可能主要通过抑制产乙酸作用来抑制甲烷生成，甲烷产量的降低幅度为10%至完全抑制，这取决于四环素浓度、接种物来源、底物组成和温度等因素。作为一种难降解污染物，四环素可在厌氧消化系统中通过吸附和生物降解去除，报道的去除效率在14.8%至90%以上。本综述系统地总结了四环素去除途径的机制，并评估了潜在贡献。易生物降解底物的共存、延长污泥停留时间以及调节pH值和温度等环境参数是提高四环素去除率的潜在策略。此外，添加导电材料已被确定为一种有前景的策略，可作为四环素吸附剂、促进种间直接电子转移并介导氧化还原反应，还可作为微生物载体以增强微生物活性。最后，本综述强调四环素胁迫下的动态响应和微生物生存策略值得进一步研究。对这些机制的更深入理解将为含四环素废水/废物处理技术的升级提供明确的理论指导。
