Takahashi Masahiro, Iwasaki Satoshi, Furutate Sakiko, Oka Shin-Ichiro, Oyamada Shogo
Department of Otorhinolaryngology, International University of Health and Welfare Mita Hospital, Tokyo, Japan.
Department of Otorhinolaryngology, International University of Health and Welfare Mita Hospital, Tokyo, Japan.
Auris Nasus Larynx. 2025 Aug;52(4):535-542. doi: 10.1016/j.anl.2025.07.008. Epub 2025 Aug 5.
The present study aimed to show the results of the advance medical care for cochlear implantation (CI) in cases of single-sided deafness.
A prospective, non-randomized, historically controlled clinical trial was conducted at a single institution from July 2021 to July 2023. Participants were patients diagnosed with unilateral, severe to profound sensorineural hearing loss and with average hearing levels over 70 dB on the poor side and under 40 dB on the better side. CI surgeries were performed through the round window approach under general anesthesia. Preoperatively and at 1, 3, 6, and 12 months after device activation, speech discrimination score was measured using the 67-S monosyllabic list under noise conditions, and sound localization ability was also assessed. Assessments of tinnitus disturbance and hearing handicap were performed using a questionnaire.
Speech discrimination score using the Japanese monosyllabic list improved significantly from preoperatively to 12 months postoperatively, and significant improvement of sound localization ability was also observed 12 months postoperatively. Tinnitus disturbance and hearing handicap according to the questionnaire were also significantly improved. All adverse events believed to be related to this treatment are well-known occurrences in CI surgery, and the risks associated with the treatment are not considered to outweigh the benefits.
The advance medical care with CI for single-sided deafness demonstrated a significant and favorable improvement using a Japanese monosyllabic list, indicating the effectiveness of the CI intervention for patients with single-sided deafness. Considering that the benefits of treatment outweigh the risks, this treatment was deemed effective for patients with single-sided deafness.
本研究旨在展示单侧耳聋患者人工耳蜗植入(CI)的先进医疗护理效果。
2021年7月至2023年7月在单一机构进行了一项前瞻性、非随机、历史对照临床试验。参与者为被诊断为单侧、重度至极重度感音神经性听力损失,患侧平均听力水平超过70分贝且较好侧低于40分贝的患者。CI手术在全身麻醉下通过圆窗入路进行。在术前以及设备激活后1、3、6和12个月,在噪声条件下使用67 - S单音节词表测量言语辨别得分,并评估声音定位能力。使用问卷对耳鸣困扰和听力障碍进行评估。
使用日语单音节词表的言语辨别得分从术前到术后12个月有显著改善,术后12个月声音定位能力也有显著提高。根据问卷评估,耳鸣困扰和听力障碍也有显著改善。所有被认为与该治疗相关的不良事件都是CI手术中常见的情况,且该治疗的风险不被认为超过益处。
单侧耳聋的CI先进医疗护理使用日语单音节词表显示出显著且良好的改善,表明CI干预对单侧耳聋患者有效。考虑到治疗的益处大于风险,该治疗对单侧耳聋患者被认为是有效的。