Zhang L, Wang G, Hou C, Cui L, Wang L, Ling X, Xu Z
Department of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2025 Aug 18;57(4):748-752. doi: 10.19723/j.issn.1671-167X.2025.04.019.
To explore the safety of laparoscopic modified transcystic biliary drainage (modified C-tube technique) in the treatment of biliary stones and application of diagnosing biliary disease.
A retrospective analysis was conducted on the clinical data of 68 cases of biliary stones successfully treated with laparoscopic modified C-tube technique from August 2021 to December 2023. The safety, effectiveness, and area of applications were analyzed. The reliability of the principle of the modified fixation method was verified by using an gallbladder.
Three cases of gallbladder demonstrated that the strength of the modified fixation method was reliable, and the sinus tract formed by suture after immediate extraction of the C tube could be dislocated and closed, resisting the bile outflow caused by the weight of the gallbladder. Among the 68 patients, 42 were difficult biliary stones, 6 were suspected common bile duct stones, and 5 were extrahepatic bile duct stones combined with intrahepatic bile duct stones. Among them, 48 cases underwent choledochoscopy assisted trans-choledochal approach for stone removal, and 10 cases underwent transcystic approach stone removal, Six patients underwent simply basket exploration and removal of stones through the cystic duct (5 patients had no residual stones on postoperative C-tube angiography, 1 patient had suspected residual stones, and the patient refused further examination and treatment for no symptom), and 4 patients only underwent biliary drainage through the cystic duct; two patients with retained stone passed after the use of topical nitrate drip infusion via C-tube, seven cases underwent endoscopic retrograde cholangiopancreatography(ERCP), stone removal with the assistance of a C-tube after laparoscopic surgery, and the results were uneventful. The mean surgical time was (131±44) min (76-279 min), the maximum daily drainage volume of the C-tube was (401±235) mL/d (10-1 150 mL/d), the hospital stay was (8.6±3.6) d (2-19 d), and the mean time of C-tube removal was (11±6.9) d (5-46 d). There were 14 overall complications, including 2 residual stones, and 12 C-tube related complications, comprising of 1 grade Ⅲa, 2 grade Ⅱ, and 9 grade Ⅰ. There were 9 cases of C-tube related adverse events that did not cause complications, including 3 of early detachment, 2 of displacement, and 4 of deep insertion. The median follow-up time after surgery was 21 (2-30) months, and 5 patients had recurrent stones. Among them, 4 patients had slow contrast outflow during cholangiogram, and 1 patient had obvious pancreaticobiliary reflux. 55 patients underwent C-tube amylase measurement, and 9 cases showed a significant increase in bile amylase (349-44 936 U/L), suggesting the presence of pancreaticobiliary reflux.
Laparoscopic modified C-tube technique can be effectively used in the treatment of biliary stones, which is relatively safe and can be attempted in the diagnosis of biliary diseases.
探讨腹腔镜改良经胆囊管胆道引流术(改良C管技术)治疗胆管结石的安全性及在胆道疾病诊断中的应用。
回顾性分析2021年8月至2023年12月采用腹腔镜改良C管技术成功治疗的68例胆管结石患者的临床资料,分析其安全性、有效性及应用范围。采用胆囊验证改良固定方法原理的可靠性。
3例胆囊验证显示改良固定方法强度可靠,C管拔除后立即缝合形成的窦道可脱位闭合,抵抗胆囊重力引起的胆汁外流。68例患者中,难取性胆管结石42例,疑似胆总管结石6例,肝外胆管结石合并肝内胆管结石5例。其中48例行胆道镜辅助经胆总管途径取石,10例行经胆囊管途径取石,6例单纯经胆囊管行网篮探查取石(5例术后C管造影无残留结石,1例疑似残留结石,患者因无症状拒绝进一步检查治疗),4例仅经胆囊管行胆道引流;2例残留结石患者经C管局部滴注硝酸酯后排出,7例行内镜逆行胰胆管造影(ERCP),腹腔镜术后借助C管取石,结果顺利。平均手术时间为(131±44)分钟(76 - 279分钟),C管最大每日引流量为(401±235)毫升/天(10 - 1150毫升/天),住院时间为(8.6±3.6)天(2 - 19天),C管拔除平均时间为(11±6.9)天(5 - 46天)。总并发症14例,其中残留结石2例,C管相关并发症12例,包括Ⅲa级1例、Ⅱ级2例、Ⅰ级9例。C管相关不良事件9例未引起并发症,包括早期脱落3例、移位2例、插入过深4例。术后中位随访时间为21(2 - 30)个月,5例复发结石。其中4例胆管造影时造影剂流出缓慢,1例胰胆反流明显。55例患者行C管淀粉酶测定,9例胆汁淀粉酶显著升高(349 - 44936 U/L),提示存在胰胆反流。
腹腔镜改良C管技术可有效用于胆管结石治疗,相对安全,可尝试用于胆道疾病诊断。