Lin Yanru, Li Qianlong
Department of Music, The School of Music and Dance, College of Chinese & ASEAN Arts, Chengdu University, Chengdu, China.
Department of Pharmaceutical Sciences, The School of Pharmacy, Wuhan University, Wuhan, China.
Front Psychol. 2025 Jul 18;16:1576381. doi: 10.3389/fpsyg.2025.1576381. eCollection 2025.
In China, Depression is a significant mental health issue among college students, with a 28.4% prevalence rate. This meta-analysis systematically synthesizes empirical data to evaluate the therapeutic efficacy of music therapy in mitigating depressive symptoms within collegiate populations.
Two authors searched seven international and Chinese databases from inception to February 5, 2025, for randomized controlled trials (RCTs) on music therapy for college students with depressive symptoms. Statistical synthesis was performed with RevMan 5.3 software, using random-effects models to calculate standardized mean differences (SMDs) with 95% confidence intervals.
Sixteen RCTs involving 938 participants were included. Pooled estimates showed significant reductions in depressive symptoms as measured by SDS (SMD = -1.19, 95% CI: -1.56 to -0.82; < 0.001), SCL-90 depression subscale (SMD = -1.29, 95% CI: -1.96 to -0.62; = 0.002), and BDI (SMD = -1.98, 95% CI: -3.59 to -0.38; = 0.015). High heterogeneity ( = 76-89%) was found, but the results remained robust even after undergoing sensitivity analyses.
Music therapy is an effective adjunctive intervention for managing depressive symptoms in college students. However, due to significant heterogeneity, future research needs standardized treatment frameworks. Multi-center RCTs with blinded assessment and longitudinal designs should be prioritized to clarify dose-response relationships and neurophysiological mechanisms, facilitating the integration of music therapy into evidence-based mental health strategies for this population.
在中国,抑郁症是大学生中一个重要的心理健康问题,患病率为28.4%。本荟萃分析系统地综合实证数据,以评估音乐疗法在减轻大学生群体抑郁症状方面的治疗效果。
两位作者检索了7个国际和中国数据库,检索时间从建库至2025年2月5日,以查找关于音乐疗法治疗有抑郁症状大学生的随机对照试验(RCT)。使用RevMan 5.3软件进行统计合成,采用随机效应模型计算标准化平均差(SMD)及95%置信区间。
纳入了16项RCT,涉及938名参与者。汇总估计显示,通过SDS(SMD = -1.19,95% CI:-1.56至-0.82;P < 0.001)、SCL-90抑郁分量表(SMD = -1.29,95% CI:-1.96至-0.62;P = 0.002)和BDI(SMD = -1.98,95% CI:-3.59至-0.38;P = 0.015)测量,抑郁症状有显著减轻。发现存在高度异质性(I² = 76 - 89%),但即使经过敏感性分析,结果仍然稳健。
音乐疗法是管理大学生抑郁症状的一种有效辅助干预措施。然而,由于存在显著异质性,未来研究需要标准化的治疗框架。应优先开展采用盲法评估和纵向设计的多中心RCT,以阐明剂量反应关系和神经生理机制,促进将音乐疗法纳入针对该人群的循证心理健康策略。