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一名25岁初产妇产后患结核性脑膜炎的不幸病例。

An Unfortunate Case of Tuberculous Meningitis in a 25-Year-Old Primigravida in the Postpartum Period.

作者信息

Kashyap Deepika

机构信息

Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS) New Delhi, New Delhi, IND.

出版信息

Cureus. 2025 Jul 3;17(7):e87220. doi: 10.7759/cureus.87220. eCollection 2025 Jul.

Abstract

Tuberculosis remains a significant global health concern, with substantial diagnostic challenges in extrapulmonary tuberculosis, particularly in vulnerable states like pregnancy and the postpartum period. The postpartum period is associated with significant immunomodulation that can predispose women to reactivation or progression of tuberculosis. A healthy 25-year-old woman who presented to the obstetrics and gynaecology department with premature rupture of membranes, delivered vaginally while being on conservative management. In the postpartum period, she developed high-grade fever with chills and headache, which progressed to altered sensorium and diplopia. The patient underwent imaging and lumbar puncture after informed consent and was diagnosed with tubercular meningitis. TB can present with non-specific symptoms. Recognition of risk factors for TB is crucial for prompt diagnosis and treatment of this deadly disease.

摘要

结核病仍然是一个重大的全球卫生问题,肺外结核存在重大诊断挑战,尤其是在怀孕和产后等脆弱状态下。产后时期与显著的免疫调节有关,这可能使女性易患结核病的复发或进展。一名健康的25岁女性因胎膜早破到妇产科就诊,在保守治疗期间经阴道分娩。产后,她出现高热、寒战和头痛,进而发展为意识改变和复视。患者在获得知情同意后接受了影像学检查和腰椎穿刺,被诊断为结核性脑膜炎。结核病可能表现为非特异性症状。识别结核病的危险因素对于及时诊断和治疗这种致命疾病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/573a/12317423/24f55d059260/cureus-0017-00000087220-i01.jpg

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