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Earlier initiation of tenofovir in pregnancy with infant hepatitis B vaccination obviates the need for hepatitis B immune globulin.

作者信息

Pak Kevin, Saab Sammy

机构信息

Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

Transl Gastroenterol Hepatol. 2025 Jun 12;10:39. doi: 10.21037/tgh-25-14. eCollection 2025.

DOI:10.21037/tgh-25-14
PMID:40755724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12314665/
Abstract
摘要

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Earlier initiation of tenofovir in pregnancy with infant hepatitis B vaccination obviates the need for hepatitis B immune globulin.孕期早期开始使用替诺福韦并对婴儿进行乙肝疫苗接种可避免使用乙肝免疫球蛋白。
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Comparative efficacy and safety of pharmacologic interventions to prevent mother-to-child transmission of hepatitis B virus: a systematic review and network meta-analysis.药物干预预防乙型肝炎病毒母婴传播的疗效和安全性比较:系统评价和网络荟萃分析。
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本文引用的文献

1
Vertical Transmission in Mothers Taking TAF With Exceptionally High Viral Load.服用替诺福韦艾拉酚胺且病毒载量极高的母亲的垂直传播
J Viral Hepat. 2025 Mar;32(3):e70000. doi: 10.1111/jvh.70000.
2
Tenofovir and Hepatitis B Virus Transmission During Pregnancy: A Randomized Clinical Trial.替诺福韦与孕期乙型肝炎病毒传播:一项随机临床试验。
JAMA. 2025 Feb 4;333(5):390-399. doi: 10.1001/jama.2024.22952.
3
Expected 8-Week Prenatal vs 12-Week Perinatal Tenofovir Alafenamide Prophylaxis to Prevent Mother-to-Child Transmission of Hepatitis B Virus: A Multicenter, Prospective, Open-Label, Randomized Controlled Trial.
比较8周孕期与12周围产期替诺福韦艾拉酚胺预防乙型肝炎病毒母婴传播的效果:一项多中心、前瞻性、开放标签、随机对照试验。
Am J Gastroenterol. 2025 May 1;120(5):1045-1056. doi: 10.14309/ajg.0000000000003122. Epub 2024 Oct 9.
4
Safety of Tenofovir Disoproxil Fumarate Among Breastfeeding Infants of Patients With Chronic Hepatitis B: A Systematic Review.替诺福韦酯二吡呋酯在慢性乙型肝炎患者母乳喂养婴儿中的安全性:系统评价。
J Viral Hepat. 2024 Nov;31(11):760-767. doi: 10.1111/jvh.14001. Epub 2024 Aug 29.
5
Hepatitis B Elimination Globally: The Answer May Not Be the Same for Everyone.全球消除乙型肝炎:答案可能因人而异。
J Pediatric Infect Dis Soc. 2024 Nov 21;13(Supplement_5):S139-S141. doi: 10.1093/jpids/piae067.
6
Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Preventing Vertical Transmission in Chronic Hepatitis B Mothers: A Systematic Review and Meta-Analysis.替诺福韦艾拉酚胺与富马酸替诺福韦二吡呋酯预防慢性乙型肝炎母亲母婴垂直传播的效果比较:系统评价与荟萃分析。
Clin Infect Dis. 2024 Oct 15;79(4):953-964. doi: 10.1093/cid/ciae288.
7
Enhancing interventions for prevention of mother-to-child- transmission of hepatitis B virus.加强预防乙型肝炎病毒母婴传播的干预措施。
JHEP Rep. 2023 Apr 24;5(8):100777. doi: 10.1016/j.jhepr.2023.100777. eCollection 2023 Aug.
8
Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study.2022年全球乙型肝炎的流行率、照护流程及预防覆盖率:一项建模研究
Lancet Gastroenterol Hepatol. 2023 Oct;8(10):879-907. doi: 10.1016/S2468-1253(23)00197-8. Epub 2023 Jul 27.
9
Global burden of hepatitis B virus: current status, missed opportunities and a call for action.全球乙型肝炎病毒负担:现状、错失的机会和行动呼吁。
Nat Rev Gastroenterol Hepatol. 2023 Aug;20(8):524-537. doi: 10.1038/s41575-023-00760-9. Epub 2023 Apr 6.
10
New Approaches to Chronic Hepatitis B.慢性乙型肝炎的新疗法
N Engl J Med. 2023 Jan 5;388(1):55-69. doi: 10.1056/NEJMra2211764.