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本文引用的文献

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Metabolism of intravenous fructose and glucose in normal and diabetic subjects.正常人和糖尿病患者体内静脉注射果糖和葡萄糖的代谢情况。
J Clin Invest. 1952 Jan;31(1):115-25. doi: 10.1172/JCI102569.
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Influence of potassium salts on efficiency of parenteral protein alimentation in the surgical patient.
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Liver adenine nucleotides: fructose-induced depletion and its effect on protein synthesis.肝脏腺嘌呤核苷酸:果糖诱导的耗竭及其对蛋白质合成的影响。
Science. 1968 Sep 20;161(3847):1253-4. doi: 10.1126/science.161.3847.1253.
4
Acute hemolytic anemia with rigid red cells in hypophosphatemia.低磷血症伴红细胞僵硬的急性溶血性贫血。
N Engl J Med. 1971 Dec 23;285(26):1446-50. doi: 10.1056/NEJM197112232852602.
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Hypophosphataemia and hyperphosphataemia in a hospital population.医院人群中的低磷血症和高磷血症
Br Med J. 1972 Jan 29;1(5795):273-6. doi: 10.1136/bmj.1.5795.273.
6
Alterations of red-cell glycolytic intermediates and oxygen transport as a consequence of hypophosphatemia in patients receiving intravenous hyperalimentation.接受静脉高营养治疗的患者因低磷血症导致红细胞糖酵解中间产物和氧运输的改变。
N Engl J Med. 1971 Sep 30;285(14):763-8. doi: 10.1056/NEJM197109302851402.
7
Hypophosphataemia in septicaemia: higher incidence in gram-negative than in gram-positive infections.败血症中的低磷血症:革兰氏阴性菌感染的发病率高于革兰氏阳性菌感染。
Br Med J. 1969 Mar 22;1(5646):753-6. doi: 10.1136/bmj.1.5646.753.
8
Intravenous essential L-amino acids and hypertonic dextrose in patients with acute renal failure. Effects on serum potassium, phosphate, and magnesium.急性肾衰竭患者静脉输注必需L-氨基酸和高渗葡萄糖。对血清钾、磷和镁的影响。
Am J Surg. 1972 Jun;123(6):632-8. doi: 10.1016/0002-9610(72)90343-1.
9
Paresthesias, weakness, seizures, and hypophosphatemia in patients receiving hyperalimentation.接受胃肠外营养的患者出现感觉异常、虚弱、癫痫发作和低磷血症。
Gastroenterology. 1972 Apr;62(4):513-20.
10
Acquired phagocyte dysfunction. A complication of the hypophosphatemia of parenteral hyperalimentation.获得性吞噬细胞功能障碍。胃肠外高营养低磷血症的一种并发症。
N Engl J Med. 1974 Jun 20;290(25):1403-7. doi: 10.1056/NEJM197406202902504.

静脉营养期间的低磷血症和磷需求

Hypophosphataemia and phosphorus requirements during intravenous nutrition.

作者信息

Tovey S J, Benton K G, Lee H A

出版信息

Postgrad Med J. 1977 Jun;53(620):289-97. doi: 10.1136/pgmj.53.620.289.

DOI:10.1136/pgmj.53.620.289
PMID:407558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2496650/
Abstract

Seven patients with acute illnesses developed hypophosphataemia whilst receiving intravenous nutrition which included a fat emulsion, Intralipid, a possible source of phosphorus. The authors' observations cast doubt on the bio-availability of the phosphorus contained in the phospholipid content of the fat emulsion. The currently recommended allowance of phosphorus for this type of patient appears to be too low and it is suggested that 0-5-0-75 mmol/kg body weight be provided, preferably as a neutral phosphate solution. Sine hypophosphataemia can occur at various time intervals after starting intravenous nutrition and precede clinical sequelae it is recommended that routine serum phosphate measurements are made in all patients receiving this treatment.

摘要

7例急性病患者在接受含脂肪乳剂(英脱利匹特,一种可能的磷来源)的静脉营养时发生了低磷血症。作者的观察结果对脂肪乳剂磷脂成分中所含磷的生物利用度提出了质疑。目前针对这类患者推荐的磷摄入量似乎过低,建议提供0.5 - 0.75 mmol/kg体重的磷,最好以中性磷酸盐溶液的形式给予。由于低磷血症可在开始静脉营养后的不同时间间隔出现,并先于临床后遗症发生,因此建议对所有接受这种治疗的患者进行常规血清磷酸盐检测。