猪肝异种移植的未来
The Future of Pig Liver Xenotransplantation.
作者信息
Karadagi Ahmad, Oniscu Gabriel C
机构信息
Division of transplantation surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Transplantation, Karolinska University Hospital, Huddinge, Sweden.
出版信息
Transpl Int. 2025 Jul 18;38:13622. doi: 10.3389/ti.2025.13622. eCollection 2025.
Abstract
Recent technological advances in genetic engineering have led to a renewed interest in xenotransplantation. Milestones achievements in heart, kidney and more recently liver xenotransplantation raise the hope of an alternative source of organs and pave the way for first in human clinical trials. With these rapid developments, it is important to consider what may be the place of liver xenotransplantation in the treatment armamentarium and what are the challenges to achieve clinical liver xenotransplantation.
摘要
基因工程领域最近的技术进步引发了人们对异种移植的新兴趣。心脏、肾脏以及最近肝脏异种移植方面的里程碑式成就，燃起了人们对替代器官来源的希望，并为首次人体临床试验铺平了道路。随着这些快速发展，重要的是要思考肝脏异种移植在治疗手段中可能占据的地位，以及实现临床肝脏异种移植面临哪些挑战。
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Transpl Int. 2025 Jul 18;38:13622. doi: 10.3389/ti.2025.13622. eCollection 2025.
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