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血栓闭塞性脉管炎肢体挽救的联合动脉重建与手术性远端静脉动脉化:病例报告

Combined Arterial Reconstruction and Surgical Distal Venous Arterialization for Limb Salvage in Thromboangiitis Obliterans: A Case Report.

作者信息

Yoshida Yuri, Kikuchi Shinsuke, Mizushima Daichi, Jinno Hirofumi, Moriyama Hiroya, Uramoto Takayuki, Takahashi Kazuki, Doita Tsutomu, Kamada Keisuke, Ohira Seima, Uchida Daiki, Kuriyama Naoya, Azuma Nobuyoshi

机构信息

Department of Vascular Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.

Department of Cardiovascular Surgery, Sapporo Kosei General Hospital, Sapporo, Hokkaido, Japan.

出版信息

Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.25-0342. Epub 2025 Jul 29.

Abstract

INTRODUCTION

Thromboangiitis obliterans (TAO) has become increasingly uncommon in Japan due to declining smoking prevalence. However, in advanced cases with severely compromised distal vasculature, achieving durable limb salvage remains a formidable surgical challenge.

CASE PRESENTATION

A 51-year-old man with a 12-year history of TAO presented with rest pain and a necrotic ulcer on the 2nd toe. He had recently ceased smoking after a 31-year history. Imaging demonstrated complete occlusion of the popliteal and tibial arteries, with foot perfusion reliant on corkscrew collaterals. The ankle-brachial index was 0.43, and skin perfusion pressure (SPP) was critically low. A severely diseased plantar artery was identified as a potential distal target. Given the high risk of graft failure, a hybrid strategy combining bypass and surgical distal venous arterialization (DVA) was preoperatively planned. To mitigate perioperative vasospasm, a lumbar sympathetic block was administered 1 week prior to surgery. An bypass using the ipsilateral great saphenous vein was constructed from the superficial femoral artery to the plantar artery. DVA was established via retrograde puncture of the plantar vein, balloon angioplasty for valve sites, and end-to-side anastomosis to the bypass graft. Early duplex ultrasonography revealed anastomotic stenosis at the DVA site as well as stenosis at valve sites, both of which were successfully managed with a single endovascular procedure. The toe stump healed completely within 3 months. The graft remained patent for 2 years, and SPP was preserved even after graft occlusion. Notably, graft failure coincided with DVA occlusion, suggesting its critical role in maintaining flow. At 42 months postoperatively, the patient remained ulcer-free with favorable perfusion, pain-free ambulation, and full return to work.

CONCLUSIONS

Preoperatively planned surgical DVA, in conjunction with sympathetic modulation and timely postoperative intervention, may offer a durable limb salvage strategy in advanced TAO with limited distal targets.

摘要

引言

由于吸烟率下降,血栓闭塞性脉管炎(TAO)在日本已变得越来越少见。然而,在远端血管严重受损的晚期病例中,实现持久的肢体挽救仍然是一项艰巨的外科挑战。

病例介绍

一名有12年TAO病史的51岁男性,出现静息痛,第二趾有坏死性溃疡。他在有31年吸烟史后最近戒烟。影像学检查显示腘动脉和胫动脉完全闭塞,足部灌注依赖于螺旋状侧支循环。踝肱指数为0.43,皮肤灌注压(SPP)极低。一条严重病变的足底动脉被确定为潜在的远端靶点。鉴于移植失败风险高,术前计划采用旁路移植术和手术性远端静脉动脉化(DVA)相结合的混合策略。为减轻围手术期血管痉挛,在手术前1周进行了腰交感神经阻滞。使用同侧大隐静脉从股浅动脉到足底动脉构建了一条旁路移植。通过足底静脉逆行穿刺、瓣膜部位球囊血管成形术以及与旁路移植的端侧吻合建立了DVA。早期双功超声检查显示DVA部位吻合口狭窄以及瓣膜部位狭窄,两者均通过单一血管内手术成功处理。趾残端在3个月内完全愈合。移植血管保持通畅2年,即使在移植血管闭塞后SPP仍得以维持。值得注意的是,移植失败与DVA闭塞同时发生,表明其在维持血流中的关键作用。术后42个月,患者溃疡愈合,灌注良好,无痛行走,完全恢复工作。

结论

术前计划的手术性DVA,结合交感神经调节和及时的术后干预,可能为远端靶点有限的晚期TAO提供一种持久的肢体挽救策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8d/12313424/91e1b424a492/scr-11-01-25-0342-g001.jpg

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