酷似多种病理实体的透明细胞牙源性癌的诊断困境：一例报告及文献综述
Diagnostic Dilemma of Clear Cell Odontogenic Carcinoma Mimicking Various Pathological Entities: A Case Report and Literature Review.
作者信息
Asiri Zayed, Alshahrani Abdullah, Hameed Mohammad Shahul, Assiri Khalil, Assiri Hassan Ahmed
机构信息
Oral and Maxillofacial Surgery Department Asir Central Hospital Abha Saudi Arabia.
Internship Program, College of Dentistry King Khalid University Abha Saudi Arabia.
出版信息
Clin Case Rep. 2025 Aug 1;13(8):e70752. doi: 10.1002/ccr3.70752. eCollection 2025 Aug.
Clear cell odontogenic carcinoma (CCOC) is an extremely rare malignancy presenting as a swelling in the mandibles of females. This disease can be diagnosed based on immunohistochemical markers, including Pan cytokeratin (CK), p63, CK5, smooth muscle actin, calponin, and S-100. Treatment can be multidisciplinary, involving surgical removal, radiotherapy, or chemotherapy.
透明细胞牙源性癌（CCOC）是一种极为罕见的恶性肿瘤，表现为女性下颌骨肿胀。这种疾病可根据免疫组化标志物进行诊断，包括全细胞角蛋白（CK）、p63、CK5、平滑肌肌动蛋白、钙调蛋白和S-100。治疗可以是多学科的，包括手术切除、放疗或化疗。
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