Pashalishvili Mariam, Zurashvili Tamar, Imerlishvili Esma, Salnikova Anna, Ompad Danielle C, Djibuti Mamuka
Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Partnership for Research and Action for Health, Tbilisi, Georgia.
BMJ Public Health. 2025 Jul 31;3(2):e002114. doi: 10.1136/bmjph-2024-002114. eCollection 2025.
This scoping review aimed to map the literature on depression and anxiety among people living with HIV and key populations in the Eastern European and Central Asian (EECA) region. The review assessed the burden of these disorders, identified inconsistencies in measurement approaches and highlighted gaps to inform future research and policy efforts.
A scoping review was conducted using Arksey and O'Malley's framework, involving a systematic search, screening and synthesis of published and grey literature in EECA Data sources: a comprehensive search was performed across five databases (CINAHL, PubMed, MEDLINE, Web of Science and PsycINFO) between July 2023 and February 2024. Additional sources were identified through Google Scholar and hand searches of reference lists from relevant research groups. Eligibility criteria: Original research articles published between January 2013 and July 2023, involving participants aged 16 years or older and reporting data from one or more EECA countries were included. Eligible studies were in English, Georgian or Russian. Excluded were reviews, editorials, treatment outcome studies, pooled data from other regions, conference materials and dissertations.
Data extraction was performed independently by team members using a Covidence template. Studies were categorised based on target populations, measurement approaches and reported prevalence of depression and anxiety. Narrative synthesis was conducted due to the heterogeneity of study designs and outcomes.
Of 3514 articles identified, 58 met inclusion criteria. Depression prevalence ranged from 8.5% to 88.0% and anxiety from 3.0% to 74.0%. Depression was assessed using 15 different scales, while anxiety was measured with eight tools. Reported prevalence exceeded global estimates, highlighting the need for targeted interventions.
The review highlights the burden of depression and anxiety in EECA, variability in measurement approaches and a lack of longitudinal and implementation research. Future efforts should standardise measurement tools, develop cohort studies and address implementation barriers to improve mental health and HIV outcomes in the region.
本范围综述旨在梳理东欧和中亚（EECA）地区艾滋病毒感染者及关键人群中抑郁症和焦虑症的相关文献。该综述评估了这些疾病的负担，确定了测量方法上的不一致之处，并突出了差距，以为未来的研究和政策努力提供参考。
采用阿克西和奥马利的框架进行范围综述，包括对EECA地区已发表和灰色文献进行系统检索、筛选和综合。数据来源：2023年7月至2024年2月期间，在五个数据库（CINAHL、PubMed、MEDLINE、科学网和PsycINFO）中进行了全面检索。通过谷歌学术搜索以及对相关研究小组参考文献列表的手工检索，确定了其他来源。纳入标准：纳入2013年1月至2023年7月发表的原创研究文章，研究对象年龄在16岁及以上，并报告来自一个或多个EECA国家的数据。符合条件的研究语言为英语、格鲁吉亚语或俄语。排除的文献包括综述、社论、治疗结果研究、来自其他地区的汇总数据、会议材料和学位论文。
团队成员使用Covidence模板独立进行数据提取。研究根据目标人群、测量方法以及报告的抑郁症和焦虑症患病率进行分类。由于研究设计和结果的异质性，进行了叙述性综合分析。
在识别出的3514篇文章中，58篇符合纳入标准。抑郁症患病率在8.5%至88.0%之间，焦虑症患病率在3.0%至74.0%之间。评估抑郁症使用了15种不同的量表，而测量焦虑症使用了8种工具。报告的患病率超过了全球估计数，凸显了针对性干预的必要性。
该综述突出了EECA地区抑郁症和焦虑症的负担、测量方法的变异性以及缺乏纵向研究和实施研究的情况。未来的努力应使测量工具标准化，开展队列研究，并解决实施障碍，以改善该地区的心理健康和艾滋病毒防治成果。
