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身体活动、焦虑、抑郁与 HIV 感染者对抗逆转录病毒治疗的依从性。

Physical Activity, Anxiety, Depression, and Adherence to Antiretroviral Therapy in People with HIV.

机构信息

Independent Researcher, Cuernavaca, Morelos, México.

Faculty of Nutrition, Autonomous University of the State of Morelos (UAEM), Cuernavaca, Morelos, Mexico.

出版信息

AIDS Res Hum Retroviruses. 2023 Jun;39(6):310-316. doi: 10.1089/AID.2022.0064. Epub 2023 Mar 29.

DOI:10.1089/AID.2022.0064
PMID:36860201
Abstract

Physical activity (PA) levels, as well as symptoms of anxiety and depression, can affect adherence to antiretroviral therapy (ART) impacting people's health. This study aimed to evaluate the association between PA levels, clinical symptoms of anxiety and depression, and adherence to ART in people living with HIV (PLHIV). A cross-sectional study, including 125 PLHIV was conducted. Adherence to ART was assessed using the Simplified Medication Adherence Questionnaire (SMAQ). For anxiety and depression, the Hospital Anxiety and Depression Scale was applied. The level of PA was assessed using the short version of the International Physical Activity Questionnaire. SPSS version 22.0 was used for statistical analysis. The prevalence of clinical levels of anxiety and depression symptoms was 53.6% and 37.6%, respectively. Fifty-three percent presented clinical levels of depression and anxiety symptoms. Sixty-one people (48.8%) had vigorous PA levels, 36 people (28.8%) had moderate PA levels, and 28 people (22.4%) had low PA levels. According to the SMAQ, 34.5% of the patients were adherent to ART. People who performed low PA levels had more risk to develop clinical levels of depression symptoms. Clinical level of anxiety, depression, and psychological distress (PD) symptoms was found to increase the risk of nonadherence to ART.

摘要

身体活动 (PA) 水平以及焦虑和抑郁症状会影响抗逆转录病毒治疗 (ART) 的依从性,从而影响人们的健康。本研究旨在评估 HIV 感染者 (PLHIV) 的 PA 水平、焦虑和抑郁的临床症状与 ART 依从性之间的关联。进行了一项包括 125 名 PLHIV 的横断面研究。采用简化用药依从性问卷 (SMAQ) 评估 ART 依从性。使用医院焦虑和抑郁量表评估焦虑和抑郁症状。采用国际体力活动问卷短版评估 PA 水平。采用 SPSS 版本 22.0 进行统计分析。临床水平焦虑和抑郁症状的患病率分别为 53.6%和 37.6%。53%的人出现临床水平的抑郁和焦虑症状。61 人(48.8%)有剧烈的 PA 水平,36 人(28.8%)有中度 PA 水平,28 人(22.4%)有低 PA 水平。根据 SMAQ,34.5%的患者对 ART 有依从性。PA 水平低的人更容易出现临床水平的抑郁症状。临床水平的焦虑、抑郁和心理困扰 (PD) 症状会增加不依从 ART 的风险。

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