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使用抗生素治疗感染性血管内移植物中1a型内漏:一例报告。

Resolution of type 1a endoleak in infected endograft using antibiotics: A case report.

作者信息

Mosienko Lucas, Dhaliwal Surinder, Guzman Randolph, Lo Evelyn, Harding Gregory

机构信息

Max Rady College of Medicine, University of Manitoba, 727 McDermot Ave Winnipeg, Manitoba R3E 3P5, Canada.

Department of Radiology, University of Manitoba, 727 McDermot Ave Winnipeg, Manitoba R3E 3P5, Canada.

出版信息

Radiol Case Rep. 2025 Jul 25;20(10):5137-5141. doi: 10.1016/j.radcr.2025.06.070. eCollection 2025 Oct.

DOI:10.1016/j.radcr.2025.06.070
PMID:40756477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12314316/
Abstract

Aortic endograft infections are associated with significant morbidity and mortality, and must be managed promptly. The definitive treatment is surgical explantation, however conservative approaches using percutaneous intervention have been shown to be successful in some cases. Notably, there is no documented case of an infected EVAR and subsequent endoleak that was managed solely by antibiotics. We present a case of a 91 year old male with an infected endograft and subsequent type 1a endoleak. He was not a surgical candidate, and a conservative approach to management was taken. Remarkably, after prolonged antibiotic therapy, both the infection and the type 1a endoleak resolved. This case suggests treating the primary endograft infection in nonsurgical candidates may also lead to the resolution of associated endoleaks. Further research is needed to understand the potential of antibiotics alone in similar cases.

摘要

主动脉腔内移植物感染与严重的发病率和死亡率相关,必须及时处理。 definitive treatment is surgical explantation, however conservative approaches using percutaneous intervention have been shown to be successful in some cases. Notably, there is no documented case of an infected EVAR and subsequent endoleak that was managed solely by antibiotics. 我们报告一例91岁男性患者,其腔内移植物感染并继发1a型内漏。他不适合手术,因此采取了保守治疗方法。值得注意的是,经过长时间的抗生素治疗后,感染和1a型内漏均得到解决。该病例表明,对非手术候选患者的原发性腔内移植物感染进行治疗,也可能导致相关内漏的消退。需要进一步研究以了解在类似病例中单独使用抗生素的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/1c67129963a9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/81df0a85a077/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/c53bdf651a36/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/4f7537252478/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/e1e188b0a376/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/1c67129963a9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/81df0a85a077/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/c53bdf651a36/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/4f7537252478/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/e1e188b0a376/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae9/12314316/1c67129963a9/gr5.jpg

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本文引用的文献

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Presentation and management of delayed aortic endograft infection.延迟性主动脉内支架移植物感染的表现和处理。
BMJ Case Rep. 2023 Mar 10;16(3):e252924. doi: 10.1136/bcr-2022-252924.
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Vasc Endovascular Surg. 2022 May;56(4):369-375. doi: 10.1177/15385744221075136. Epub 2022 Feb 18.
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Management of abdominal aortic prosthetic graft and endograft infections. A multidisciplinary update.腹主动脉假体移植物和血管内移植物感染的处理。多学科更新。
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Endovascular Aneurysm Repair Complicated with Type Ia Endoleak and Presumable Infection Treated with a Fenestrated Endograft.血管内动脉瘤修复术合并Ia型内漏及疑似感染,采用开窗型血管内移植物治疗。
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