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创伤性椎动脉损伤后后循环卒中的发病率及预后:一项为期6年的单中心回顾性队列研究。

Incidence and outcomes of posterior circulation stroke following traumatic vertebral artery injury: A 6-year single-center retrospective cohort study.

作者信息

Sterne Jonathan, McLorinan Greg

机构信息

Department of Spinal Surgery, Royal Victoria Hospital, Belfast, Ireland.

出版信息

J Craniovertebr Junction Spine. 2025 Apr-Jun;16(2):176-179. doi: 10.4103/jcvjs.jcvjs_7_25. Epub 2025 Jul 3.

DOI:10.4103/jcvjs.jcvjs_7_25
PMID:40756498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12313043/
Abstract

OBJECTIVES

Vertebral artery injury (VAI) is an uncommon, but potentially devastating, complication following cervical spine trauma. Posterior circulation ischemia (POCS) can result from a disruption to the vertebral arteries and potentially lead to long-term morbidity and mortality for these patients. This study aimed to describe the outcomes for patients with POCS as a result of VAI.

METHODS

Six hundred and twenty patients who sustained a cervical spine fracture with or without dislocation were identified from the years 2011 to 2017. Demographic data, injury details, and imaging results were collected with inpatient and outpatient records on the regional electronic care record. Patients with VAI were identified (n = 20) and screened for subsequent POCS. Their outcome was recorded from inpatient and outpatient records.

RESULTS

POCS was identified in 6 patients who had sustained a VAI (30%). Of those 6 patients, 5 had long-term neurological deficits following their injury and POCS. Two patients died within 30 days and 3 patients had died by 60 days following injury.

CONCLUSIONS

POCS occurred in 30% of patients who sustained a VAI in this study. It carried significant morbidity and mortality for the patients who suffered this potentially devastating complication. Clinicians involved in the care of patients with cervical spine trauma should be aware of the risk factors for VAI and ensure to be suspicious of POCS in patients who have proven VAI.

摘要

目的

椎动脉损伤(VAI)是颈椎创伤后一种不常见但可能具有毁灭性的并发症。椎动脉中断可导致后循环缺血(POCS),并可能给这些患者带来长期的发病率和死亡率。本研究旨在描述因VAI导致POCS患者的预后情况。

方法

从2011年至2017年期间确定了620例发生颈椎骨折伴或不伴脱位的患者。通过区域电子护理记录中的住院和门诊记录收集人口统计学数据、损伤细节和影像学结果。确定了VAI患者(n = 20),并对其随后的POCS进行筛查。从住院和门诊记录中记录他们的预后情况。

结果

在20例VAI患者中有6例被确定发生POCS(30%)。在这6例患者中,5例在受伤和发生POCS后出现长期神经功能缺损。2例患者在30天内死亡,3例患者在受伤后60天内死亡。

结论

在本研究中,30%的VAI患者发生了POCS。对于遭受这种潜在毁灭性并发症的患者,它带来了显著的发病率和死亡率。参与颈椎创伤患者护理的临床医生应了解VAI的危险因素,并确保对已证实发生VAI的患者怀疑有POCS。

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本文引用的文献

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The Incidence, Characteristics and Outcomes of Vertebral Artery Injury Associated with Cervical Spine Trauma: A Systematic Review.颈椎创伤相关椎动脉损伤的发生率、特征及预后:一项系统综述
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Vertebral Artery Injury in Cervical Spine Fractures: A Cohort Study and Review of the Literature.颈椎骨折中的椎动脉损伤:一项队列研究及文献回顾。
Ulster Med J. 2020 Sep;89(2):89-94. Epub 2020 Oct 21.
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Vertebral Artery Injury with Coinciding Unstable Cervical Spine Trauma: Mechanisms, Evidence-based Management, and Treatment Options.椎动脉损伤合并颈椎不稳定创伤:机制、循证管理及治疗选择
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Cervical Spine Fractures: Who Really Needs CT Angiography?颈椎骨折:谁真正需要 CT 血管造影?
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Contemporary outcomes of vertebral artery injury.当代椎动脉损伤的结果。
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Vertebral artery injury in destabilized midcervical spine trauma; predisposing factors and proposed mechanism.不稳定型颈中脊柱创伤中的椎动脉损伤;易患因素和拟议的发病机制。
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