DeNardo G L, DeNardo S J, Carretta R F, Bogren H G, Jansholt A L, Krohn K A, Peek N F
Clin Nucl Med. 1985 Dec;10(12):880-3. doi: 10.1097/00003072-198512000-00013.
In 40 patients believed to have deep venous thrombosis, bioscintigrams performed with I-123 fibrinogen were available for comparison with either contrast venograms or I-125 fibrinogen uptake tests. If either contrast venography or the fibrinogen uptake test was accepted as a standard for comparison, the accuracy of bioscintigraphic imaging was 90%. Most discrepancies between the procedures could be interpreted as due to heparin treatment, although bioscintigrams often were positive in patients treated with heparin for a short interval of time. Additionally, bioscintigrams provided information to distinguish venous thrombosis from other sources for local accumulation of radioactivity. Bioscintigraphy seems to be a promising noninvasive method for the detection of deep venous thrombosis of the lower extremities.
在40例被认为患有深静脉血栓形成的患者中，可获得用I-123纤维蛋白原进行的生物闪烁扫描图，以便与静脉造影或I-125纤维蛋白原摄取试验进行比较。如果将静脉造影或纤维蛋白原摄取试验中的任何一项作为比较标准，生物闪烁扫描成像的准确性为90%。尽管在短期接受肝素治疗的患者中生物闪烁扫描图常呈阳性，但这些检查方法之间的大多数差异可解释为与肝素治疗有关。此外，生物闪烁扫描图能提供信息，以区分静脉血栓形成与其他导致局部放射性聚集的来源。生物闪烁扫描似乎是一种很有前景的用于检测下肢深静脉血栓形成的非侵入性方法。
