Prescott S M, Tikoff G, Coleman R E, Richards K L, Armstrong J D, Hershgold E L, McDaniel D C, Ganchan R P
AJR Am J Roentgenol. 1978 Sep;131(3):451-3. doi: 10.2214/ajr.131.3.451.
Autologous 131I-labeled fibrinogen was administered to 17 patients during 19 episodes of suspected lower extremity deep vein thrombosis in an attempt to assess its diagnostic accuracy. Serial rectilinear scanning and probe counting of the lower extremities and pelvis were performed and compared with ascending contrast venography. The sensitivities of imaging and counting were 67% and 47%, respectively, and both had a specificity of 95%. The experience with evaluation of deep vein thrombosis of the pelvic and iliac veins was small but suggested that 131I fibrinogen will be of limited use in those vessels.
对17例患者在19次疑似下肢深静脉血栓形成发作期间给予自体131I标记的纤维蛋白原，以评估其诊断准确性。对下肢和骨盆进行连续直线扫描和探头计数，并与上行静脉造影进行比较。成像和计数的敏感性分别为67%和47%，两者的特异性均为95%。对盆腔和髂静脉深静脉血栓形成的评估经验较少，但提示131I纤维蛋白原在这些血管中的应用有限。
