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超高分子量聚乙烯(UHMWPE)植入物在眼眶骨折重建中的评估:一项多中心队列研究。

Evaluation of Ultra-High Molecular Weight Polyethylene (UHMWPE) Implants in Orbital Fracture Reconstruction: A Multicenter Cohort Study.

作者信息

Afxentiou Konstantinos, Preidl Raimund H M, Kesting Marco R, Aksu Adem, von Bomhard Achim, Pippich Katharina, Wilhelm Stefanie, Lutz Rainer

机构信息

Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.

Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

出版信息

J Maxillofac Oral Surg. 2025 Aug;24(4):1137-1143. doi: 10.1007/s12663-025-02618-w. Epub 2025 Jul 5.

DOI:10.1007/s12663-025-02618-w
PMID:40756907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12316613/
Abstract

PURPOSE

Orbital wall reconstruction remains a challenge in reconstructive CMF surgery due to the delicate anatomical structures and their potential functional impairment due to inefficient treatment. The use of biomaterials in reconstructive surgery has revolutionised the therapy in this area. Ultra-high molecular weight polyethylene (UHMWPE) has shown promising results due to its biocompatibility, mechanical properties, and versatility. This paper presents the first clinical study of the use of UHMWPE in orbital fracture reconstruction.

METHODS

In a multicentre prospective study consisting of 50 patients undergoing orbital floor reconstruction, UHMWPE implants were used to reconstruct the orbital volume after fracture. 46 Patients underwent preoperative and postoperative 3D radiography and orbital volume segmentation.

RESULTS

A significant postoperative volume reduction of the affected orbits was observed in the entire cohort ( < 0.001) with a significant alignment to the healthy contralateral orbits. There were no implant-related complications.

CONCLUSION

Orbital wall reconstruction with UHMWPE (marPOR) implants is a reliable method to restore adequate orbital volume for functional and aesthetic recovery in trauma patients.

摘要

目的

由于眼眶壁解剖结构精细,且治疗不当可能导致功能受损,眼眶壁重建在颅颌面重建手术中仍然是一项挑战。生物材料在重建手术中的应用彻底改变了该领域的治疗方法。超高分子量聚乙烯(UHMWPE)因其生物相容性、机械性能和多功能性而显示出有前景的结果。本文介绍了使用UHMWPE进行眼眶骨折重建的首例临床研究。

方法

在一项多中心前瞻性研究中,50例患者接受了眶底重建,使用UHMWPE植入物在骨折后重建眼眶容积。46例患者在术前和术后进行了三维放射摄影和眼眶容积分割。

结果

在整个队列中观察到患侧眼眶术后容积显著减小(<0.001),且与对侧健康眼眶显著对齐。未出现与植入物相关的并发症。

结论

使用UHMWPE(marPOR)植入物进行眼眶壁重建是一种可靠的方法,可为创伤患者恢复足够的眼眶容积,以实现功能和美学恢复。

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本文引用的文献

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Indian J Ophthalmol. 2025 Feb 1;73(2):191-198. doi: 10.4103/IJO.IJO_1100_24. Epub 2025 Jan 24.
2
Ultra-High Molecular Weight Polyethylene (marPOR) is a Suitable Material for the Reconstruction of Orbital Floor Fracture Defects in Human Cadavers.超高分子量聚乙烯(marPOR)是用于人体尸体眼眶底骨折缺损修复的合适材料。
J Maxillofac Oral Surg. 2024 Dec;23(6):1646-1652. doi: 10.1007/s12663-022-01789-0. Epub 2022 Sep 28.
3
Reconstruction of Orbital Floor Fractures with Titanium Micromesh: Our Experience.
钛微网修复眶底骨折:我们的经验
J Maxillofac Oral Surg. 2022 Jun;21(2):369-378. doi: 10.1007/s12663-020-01407-x. Epub 2020 Jul 9.
4
Quantitative assessment of increase in orbital volume after orbital floor fracture reconstruction using a bioabsorbable implant.采用可吸收植入物评估眶底骨折重建术后眶容积增加的定量评估。
Graefes Arch Clin Exp Ophthalmol. 2022 Sep;260(9):3027-3036. doi: 10.1007/s00417-022-05610-z. Epub 2022 Mar 9.
5
Ultra-high molecular weight polyethylene (UHMWPE) for hip and knee arthroplasty: The present and the future.用于髋关节和膝关节置换术的超高分子量聚乙烯(UHMWPE):现状与未来。
J Orthop. 2021 Apr 23;25:98-106. doi: 10.1016/j.jor.2021.04.004. eCollection 2021 May-Jun.
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Clinical evaluation of the efficacy of materials used for primary reconstruction of orbital floor defects: Meta-analysis.临床评价用于眶底缺损初次重建的材料的疗效:荟萃分析。
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7
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