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颅内动脉粥样硬化性狭窄中血流动力学分析与传统成像的整合:现状与未来展望。

Integrating hemodynamic analysis with traditional imaging in intracranial atherosclerotic stenosis: current status and future perspectives.

作者信息

Yin Xulong, Yang Rui, Li Zhen, Wang Hui, Fang Qi

机构信息

Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Institute of Stroke Research, Soochow University, Suzhou, China.

出版信息

Front Neurol. 2025 Jul 18;16:1589162. doi: 10.3389/fneur.2025.1589162. eCollection 2025.

Abstract

Intracranial atherosclerotic stenosis (ICAS) is a significant cause of ischemic stroke. Traditional imaging methods have their own advantages and disadvantages in the diagnosis of ICAS. Hemodynamic analysis technology, as a new technique and method based on conventional imaging examinations, when combined with traditional imaging, can more comprehensively assess the hemodynamic status of ICAS patients, providing a new direction for the diagnosis and research of ICAS. This review provides an overview of the traditional imaging techniques currently used to diagnose ICAS, including transcranial Doppler ultrasound (TCD), computed tomography angiography (CTA), magnetic resonance angiography (MRA), high-resolution magnetic resonance imaging, and digital subtraction angiography (DSA). The unique characteristics of each method are elaborated. In addition, examples of hemodynamic analysis applications based on these traditional imaging techniques are discussed. This article summarizes and reviews the prospects and limitations of ICAS hemodynamic analysis and proposes potential directions for future research. As a recently developed clinical evaluation method for ICAS, hemodynamic analysis techniques have demonstrated significant potential in various aspects of ICAS, including clinical diagnosis, etiological exploration, treatment selection, and recurrence prediction. It is hoped that the method of hemodynamic analysis will ultimately be incorporated into the treatment guidelines for ICAS patients, paving new ways for the diagnosis and treatment of ICAS.

摘要

颅内动脉粥样硬化性狭窄(ICAS)是缺血性卒中的重要病因。传统成像方法在ICAS诊断中各有优缺点。血流动力学分析技术作为基于传统成像检查的新技术和方法,与传统成像相结合时,能够更全面地评估ICAS患者的血流动力学状态,为ICAS的诊断和研究提供新方向。本文综述了目前用于诊断ICAS的传统成像技术,包括经颅多普勒超声(TCD)、计算机断层血管造影(CTA)、磁共振血管造影(MRA)、高分辨率磁共振成像和数字减影血管造影(DSA)。阐述了每种方法的独特特点。此外,还讨论了基于这些传统成像技术的血流动力学分析应用实例。本文总结并回顾了ICAS血流动力学分析的前景和局限性,并提出了未来研究的潜在方向。作为一种最近开发的ICAS临床评估方法,血流动力学分析技术在ICAS的各个方面,包括临床诊断、病因探索、治疗选择和复发预测,都显示出巨大潜力。希望血流动力学分析方法最终能纳入ICAS患者的治疗指南,为ICAS的诊断和治疗开辟新途径。

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