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结肠癌穿孔继发腹部坏死性筋膜炎

Abdominal Necrotizing Fasciitis Secondary to Perforated Colon Cancer.

作者信息

Devkota Anirudra, Shrestha Anish, Bilalaga Mariah M, Gaddipati Greeshma, Haas Christopher J

机构信息

Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.

Department of Internal Medicine, Georgetown University School of Medicine, Washington, D.C., USA.

出版信息

J Community Hosp Intern Med Perspect. 2025 Jul 3;15(4):73-76. doi: 10.55729/2000-9666.1516. eCollection 2025.

DOI:10.55729/2000-9666.1516
PMID:40757215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12315888/
Abstract

Necrotizing Fasciitis (NF) is a severe, potentially fatal soft tissue infection leading to death of muscles, fascia, and surrounding tissue. Perforated colon cancer (CC) is an exceedingly uncommon cause of NF. Here, we present a case of NF secondary to perforated colon cancer. This case emphasizes the significance of prompt identification, aggressive surgical excision of affected tissue, and consideration of rare, yet potentially fatal underlying etiologies in the management of NF as well as underscores the importance of CC screening to prevent devastating complications and mortality.

摘要

坏死性筋膜炎(NF)是一种严重的、可能致命的软组织感染,可导致肌肉、筋膜及周围组织坏死。穿孔性结肠癌(CC)是NF极为罕见的病因。在此,我们报告一例继发于穿孔性结肠癌的NF病例。该病例强调了在NF治疗中迅速识别、积极手术切除受累组织以及考虑罕见但可能致命的潜在病因的重要性,同时也凸显了CC筛查对于预防严重并发症和死亡的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/1cf1d115719f/jchim-15-04-073f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/8b613208a337/jchim-15-04-073f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/7e13c776b7e4/jchim-15-04-073f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/1cf1d115719f/jchim-15-04-073f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/8b613208a337/jchim-15-04-073f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/7e13c776b7e4/jchim-15-04-073f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/12315888/1cf1d115719f/jchim-15-04-073f3.jpg

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本文引用的文献

1
Lower extremity necrotizing fasciitis with iliopsoas abscess secondary to perforated colon cancer: a diagnosis not to miss.结肠癌穿孔继发下肢坏死性筋膜炎伴髂腰肌脓肿:不容错过的诊断。
J Surg Case Rep. 2023 Dec 30;2023(12):rjad685. doi: 10.1093/jscr/rjad685. eCollection 2023 Dec.
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Necrotizing fasciitis: an update on epidemiology, diagnostic methods, and treatment.坏死性筋膜炎:流行病学、诊断方法和治疗的最新进展。
Curr Opin Infect Dis. 2024 Apr 1;37(2):105-111. doi: 10.1097/QCO.0000000000000988. Epub 2023 Nov 30.
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一例继发于结肠癌穿孔的坏死性软组织感染病例。
Cureus. 2021 Sep 2;13(9):e17663. doi: 10.7759/cureus.17663. eCollection 2021 Sep.
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Perforated colorectal cancers: clinical outcomes of 18 patients who underwent emergency surgery.穿孔性结直肠癌:18例行急诊手术患者的临床结局
Prz Gastroenterol. 2021;16(2):161-165. doi: 10.5114/pg.2021.106667. Epub 2021 Jun 4.
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J Surg Case Rep. 2020 Nov 10;2020(11):rjaa371. doi: 10.1093/jscr/rjaa371. eCollection 2020 Nov.
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Surgical management of a perforated caecal carcinoma presenting as abdominal wall necrotizing fasciitis.以腹壁坏死性筋膜炎为表现的盲肠穿孔癌的外科治疗
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Necrotizing fasciitis of the thigh due to penetrated descending colon cancer: a case report.降结肠癌穿透致大腿坏死性筋膜炎:一例报告
Surg Case Rep. 2018 Nov 26;4(1):136. doi: 10.1186/s40792-018-0544-y.
8
Bowel Perforation Resulting in Necrotizing Soft-Tissue Infection of the Abdomen, Flank, and Lower Extremities.肠穿孔导致腹部、侧腹和下肢坏死性软组织感染。
Surg Infect (Larchmt). 2018 Jul;19(5):467-472. doi: 10.1089/sur.2018.022. Epub 2018 Jun 12.
9
Colon cancer with perforation.伴有穿孔的结肠癌
Surg Today. 2019 Jan;49(1):15-20. doi: 10.1007/s00595-018-1661-8. Epub 2018 Apr 24.
10
Deaths from necrotizing fasciitis in the United States, 2003-2013.2003年至2013年美国坏死性筋膜炎导致的死亡情况。
Epidemiol Infect. 2016 Apr;144(6):1338-44. doi: 10.1017/S0950268815002745. Epub 2015 Nov 9.