Siddiqui Hafiz Umair, Isaacson Dylan, Refaai Khaled, Lin Yi-Chia, Venkatesh Krishnamurthi, Wee Alvin, Eltemamy Mohamed
Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Urology, Cleveland Clinic, Weston, Florida, USA.
J Endourol. 2025 Aug 1. doi: 10.1089/end.2025.0308.
Ureteral stricture after renal transplantation has a reported incidence of 1.4%-4.7%. This is classically repaired using an open surgical approach. The objective of this case series is to demonstrate the feasibility and effectiveness of robot-assisted repair for ureteral stricture following kidney transplantation. Between November 2021 and May 2024, 10 patients underwent robot-assisted repair. Nephrostomy tubes were placed in all patients prior to the robotic repair. Patients were positioned supine with Trendelenburg tilt, and robotic ports were arranged in a W configuration. Indocyanine green was administered through the nephrostomy tube. If necessary, the pre-stented native ureter was identified and dissected. The reconstructive technique was tailored to the location and length of the stricture. Ureteral stents were placed for 4-6 weeks. Patient demographics transplant characteristics, and details of stricture repair techniques along with associated outcomes were analyzed. Strictures were located at the ureterovesical anastomosis in eight patients, at the ureteropelvic junction in one patient, and at multiple sites in one patient. Repair techniques included ureteroneocystostomy (five patients) and Boari flap reconstruction (two patients). The native ureter was used in three patients (two ureteroureterostomies and one ureteropyelostomy). A bladder hitch was performed in two patients. Median operative time was 255.5 minutes, blood loss was 62 mL, and the hospital stay was 2 days. Postoperative complications occurred in two patients, and five patients required readmission within 30 days. At 3-month follow-up, all patients had excellent renal allograft function (median serum creatinine = 1.63 mg/dL) and were nephrostomy tube- and stent-free. Robotic repair of ureteral stricture following kidney transplantation is a safe, minimally invasive approach with reduced postoperative pain and shorter hospital stays. This approach should be considered the primary treatment option for renal transplant ureteral strictures and included within the renal transplant surgeons' repertoire of procedures.
肾移植术后输尿管狭窄的报道发生率为1.4%-4.7%。传统上采用开放手术方法进行修复。本病例系列的目的是证明机器人辅助修复肾移植术后输尿管狭窄的可行性和有效性。在2021年11月至2024年5月期间,10例患者接受了机器人辅助修复。在机器人修复前,所有患者均放置了肾造瘘管。患者取仰卧位,头低脚高位,机器人端口呈W形排列。通过肾造瘘管注入吲哚菁绿。如有必要,识别并解剖预先置入支架的自体输尿管。重建技术根据狭窄的位置和长度进行调整。输尿管支架放置4-6周。分析了患者的人口统计学、移植特征、狭窄修复技术细节及相关结果。8例患者的狭窄位于输尿管膀胱吻合处,1例患者位于输尿管肾盂连接处,1例患者位于多个部位。修复技术包括输尿管膀胱再植术(5例患者)和Boari瓣重建术(2例患者)。3例患者使用了自体输尿管(2例输尿管输尿管吻合术和1例输尿管肾盂吻合术)。2例患者进行了膀胱固定术。中位手术时间为255.5分钟,失血量为62毫升,住院时间为2天。2例患者发生术后并发症,5例患者在30天内需要再次入院。在3个月的随访中,所有患者的同种异体肾移植功能良好(中位血清肌酐=1.63mg/dL),且无肾造瘘管和支架。肾移植术后输尿管狭窄的机器人修复是一种安全、微创的方法,术后疼痛减轻,住院时间缩短。这种方法应被视为肾移植输尿管狭窄的主要治疗选择,并纳入肾移植外科医生的手术范围。