Zhang Yingkai, Ge Zhe, Gu Yutong, Cai Guoping
Department of Orthopaedic Surgery, Jinshan Hospital, Fudan University, Shanghai City, 201508, P.R. China.
Department of Orthopaedic Surgery, Zhongshan Hospital Fudan University, Shanghai City, 200032, P.R. China.
BMC Surg. 2025 Aug 4;25(1):338. doi: 10.1186/s12893-025-02993-8.
This study aimed to compare the clinical efficacy of anterior cervical discectomy and fusion (ACDF) with self-lock cage through mini-incision, ACDF with cage and plate, and posterior laminoplasty (LAMP) for long-level cervical spondylosis without severe ossification of posterior longitudinal ligament.
From January 2018 to January 2021, patients diagnosed with 3-4 segments (C3-7) cervical spondylotic radiculopathy, cervical spondylotic myelopathy, or mixed cervical spondylosis underwent surgical treatment. The procedures included ACDF with self-lock cage through mini-incision (48 cases) (group A), ACDF with cage and plate (37 cases) (group B), and LAMP (40 cases) (group C). Surgical parameters such as operative time, blood loss, incision length, and hospital stay were documented. Additionally, measurements were taken for intervertebral height, functional segment height, cervical lordosis, cervical hyperextension and hyperflexion range-of-motion (ROM), and ROM in all directions of the cervical spine before and after surgery. The therapeutic outcomes of both groups were evaluated, and any postoperative complications were meticulously recorded.
There was no significant difference in gender, age, JOA, VAS score of upper limb, NDI score, preoperative cervical intervertebral height, functional segment height, lordosis angle, cervical ROM, hyperextension and hyperflexion ROM was observed among three groups. The patients in group A and group B had less bleeding, shorter incision, and fewer hospitalization days than group C (P < 0.05). The patients in group A had a shorter incision than those in group B (P < 0.05). Group A showed shortest operation time(A < B < C)(P < 0.05). There was no significant difference in JOA, VAS score of upper limb, NDI score after surgery among three groups. The restoration of postoperative intervertebral height, functional segment height, and cervical lordosis angle of group A and group B were significantly more than those of group C (P < 0.05). There was no significant difference between preoperative and postoperative ROM in all directions of cervical spine in three groups.
All three surgical techniques-self-locking cage ACDF, cage-and-plate ACDF, and LAMP-are effective options for treating long-level cervical spondylosis without severe OPLL. Among them, the self-locking cage technique offers distinct advantages, including smaller incisions, less surgical trauma, a lower risk of postoperative dysphagia, and a high fusion rate even in multilevel procedures.
本研究旨在比较小切口自锁椎间融合器前路颈椎间盘切除融合术(ACDF)、带椎间融合器和钢板的ACDF以及后路椎板成形术(LAMP)治疗无严重后纵韧带骨化的长节段颈椎病的临床疗效。
2018年1月至2021年1月,对诊断为3 - 4节段(C3 - 7)神经根型颈椎病、脊髓型颈椎病或混合型颈椎病的患者进行手术治疗。手术方式包括小切口自锁椎间融合器ACDF(48例)(A组)、带椎间融合器和钢板的ACDF(37例)(B组)以及LAMP(40例)(C组)。记录手术时间、出血量、切口长度和住院时间等手术参数。此外,在手术前后测量椎间高度、功能节段高度、颈椎前凸、颈椎过伸和过屈活动度(ROM)以及颈椎各方向的ROM。评估两组的治疗效果,并详细记录任何术后并发症。
三组患者在性别、年龄、日本骨科学会(JOA)评分、上肢视觉模拟评分(VAS)、颈部功能障碍指数(NDI)评分、术前颈椎椎间高度、功能节段高度、前凸角、颈椎ROM、过伸和过屈ROM方面均无显著差异。A组和B组患者的出血量、切口长度和住院天数均少于C组(P < 0.05)。A组患者的切口比B组短(P < 0.05)。A组手术时间最短(A < B < C)(P < 0.05)。三组术后JOA评分、上肢VAS评分、NDI评分无显著差异。A组和B组术后椎间高度、功能节段高度和颈椎前凸角的恢复明显优于C组(P < 0.05)。三组颈椎各方向术前和术后ROM无显著差异。
自锁椎间融合器ACDF、带椎间融合器和钢板的ACDF以及LAMP这三种手术技术都是治疗无严重后纵韧带骨化的长节段颈椎病的有效选择。其中,自锁椎间融合器技术具有明显优势,包括切口小、手术创伤小、术后吞咽困难风险低,即使在多节段手术中融合率也高。