Lindert Jutta, Arndt Sarah, Cook Natalie, Bain Paul A, Kawachi Ichiro
Department of Social Work and Health, University of Applied Sciences Emden/Leer, Emden, Germany.
Leeds and York Partnership NHS Foundation Trust, Leeds, United Kingdom.
Public Health Rev. 2025 Jul 21;46:1607381. doi: 10.3389/phrs.2025.1607381. eCollection 2025.
We aim to investigate the association between family relationships and mental health conditions in adults aged 18+.
We conducted a systematic review on associations of family relationships and mental health conditions by searching in databases MEDLINE, Embase, Web of Science Core Collection, PsycINFO, Sociological Abstracts (ProQuest), and PTSDPubs. We calculated the Pearson correlation coefficients and I2 statistics using a random-effects model. Additionally, we investigated publication bias using funnel plots.
Of the 3,707 records screened, 40 with n = 35,634 participants met the inclusion criteria (38.5% male, 59.5% female, mean age 39.57), were conducted mostly in North America (n = 27). Positive family relationships were investigated in 33 studies, negative relationships in 12 studies. Positive family relationships were not statistically significantly associated with depression [r = -0.071 (-0.256, 0.119), p = 0.463, anxiety r = 0.026 (-0.032, 0.084), p = 0.375] or alcohol abuse [r = 0.035 (-0.103, 0.0034), p=0.326]. Positive family relationships were statistically significantly associated with illicit drug use [r = 0.061 (0.025, 0.096), p = 0.001]. Negative family relationships were statistically significantly associated with anxiety [r = 0.075 (0.019, 0.130), p = 0.009], and with depression [r = 0.111 (0.033, 0.188), p = 0.005].
Interventions reducing negative family relationships can potentially strengthen positive mental health.
我们旨在调查18岁及以上成年人的家庭关系与心理健康状况之间的关联。
我们通过检索MEDLINE、Embase、科学网核心合集、PsycINFO、社会学文摘（ProQuest）和PTSDPubs数据库，对家庭关系与心理健康状况的关联进行了系统综述。我们使用随机效应模型计算了Pearson相关系数和I²统计量。此外，我们使用漏斗图研究了发表偏倚。
在筛选的3707条记录中，40项研究（n = 35634名参与者）符合纳入标准（男性占38.5%，女性占59.5%，平均年龄39.57岁），大部分研究在北美进行（n = 27）。33项研究调查了积极的家庭关系，12项研究调查了消极的家庭关系。积极的家庭关系与抑郁症[r = -0.071（-0.256，0.119），p = 0.463]、焦虑症[r = 0.026（-0.032，0.084），p = 0.375]或酒精滥用[r = 0.035（-0.103，0.0034），p = 0.326]无统计学显著关联。积极的家庭关系与非法药物使用有统计学显著关联[r = 0.061（0.025，0.096），p = 0.001]。消极的家庭关系与焦虑症[r = 0.075（0.019，0.130），p = 0.009]和抑郁症[r = 0.111（0.033，0.188），p = 0.005]有统计学显著关联。
减少消极家庭关系的干预措施可能会增强积极的心理健康。
