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针对注意力缺陷多动障碍(ADHD)及其伴随损伤的校本随机对照试验:一项系统评价与荟萃分析。

School-based randomized controlled trials for ADHD and accompanying impairments: a systematic review and meta-analysis.

作者信息

Yegencik Beliz, Bell Beth T, Deniz Emre

机构信息

Department of Education, The University of York, York, United Kingdom.

出版信息

Front Psychol. 2025 Jul 21;16:1611145. doi: 10.3389/fpsyg.2025.1611145. eCollection 2025.

Abstract

INTRODUCTION

Children and young people with Attention Deficit Hyperactivity Disorder (ADHD) face disproportionate challenges due to core symptoms of ADHD (i.e., inattention and hyperactivity) interfering with academic, social, and behavioural functioning. The significant rise in the prevalence of ADHD and difficulties experienced by children and young people over recent years has put a lot more emphasis on school-based interventions. Despite this, and the tremendous amount of randomised controlled trials (RCTs) reporting school-based interventions for ADHD over the past decades, there has been no systematic reporting of the pooled effects of such trials in the literature.

METHODS

This study seeks, for the first time, to report the effects of school-based RCTs on the core symptoms of ADHD and other difficulties, i.e., academic, social, emotional and behavioural (i.e., externalising). Search was performed in three journals, for interventions from 1980 to 2024 that targeted school-aged children (4 to 18 years old) with ADHD.

RESULTS

In total, 26 randomised controlled trials met the inclusion criteria, 22 (n = 1962) of which were included in our meta-analyses. Our findings showed that school-based based randomised controlled trials were effective in improving combined ADHD ( = -0.28,  < 0.0001), inattention ( = -0.33,  < 0.0001), academic performance ( = 0.37,  < 0.0001), and social skills ( = 0.28,  < 0.001), and reducing externalising problems ( = -0.32,  = 0.001). There was no significant effect for hyperactivity/impulsivity ( = -0.09,  = 0.22).

DISCUSSION

Our findings showed that school-based randomised controlled trials improve a range of difficulties experienced by children and young people with ADHD, but lack focus on hyperactivity/impulsivity. Future interventions would benefit from a more comprehensive focus on hyperactivity/impulsivity for system-wide improvement. Issues related to high levels of heterogeneity and potential reporter bias are further discussed.

摘要

引言

患有注意力缺陷多动障碍(ADHD)的儿童和青少年面临着不成比例的挑战,因为ADHD的核心症状(即注意力不集中和多动)会干扰学业、社交和行为功能。近年来,ADHD患病率的显著上升以及儿童和青少年所经历的困难,使得人们更加重视基于学校的干预措施。尽管如此,在过去几十年中,大量随机对照试验(RCT)报告了针对ADHD的基于学校的干预措施,但文献中尚未对这些试验的综合效果进行系统报告。

方法

本研究首次旨在报告基于学校的随机对照试验对ADHD核心症状及其他困难(即学业、社交、情感和行为方面,即外化问题)的影响。在三本期刊中进行检索,查找1980年至2024年针对患有ADHD的学龄儿童(4至18岁)的干预措施。

结果

共有26项随机对照试验符合纳入标准,其中22项(n = 1962)纳入了我们的荟萃分析。我们的研究结果表明,基于学校的随机对照试验在改善综合ADHD( =  -0.28,  < 0.0001)、注意力不集中( =  -0.33,  < 0.0001)、学业成绩( = 0.37,  < 0.0001)和社交技能( = 0.28,  < 0.001)以及减少外化问题( =  -0.32,  = 0.001)方面是有效的。多动/冲动方面没有显著效果( =  -0.09,  = 0.22)。

讨论

我们的研究结果表明,基于学校的随机对照试验改善了患有ADHD的儿童和青少年所经历的一系列困难,但缺乏对多动/冲动的关注。未来的干预措施若能更全面地关注多动/冲动,将有助于实现全系统的改善。还进一步讨论了与高度异质性和潜在报告偏倚相关的问题。

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