Samsuddin Sofeah, Leong Lester Chee Hao, Lim Cheryl Hui Shan, Wong Chow Yin, Tan Ying Ching
Department of Breast Surgery, Singapore General Hospital, Singapore, SGP.
Department of Diagnostic Radiology, Singapore General Hospital, Singapore, SGP.
Cureus. 2025 Jul 5;17(7):e87336. doi: 10.7759/cureus.87336. eCollection 2025 Jul.
Granular cell tumours (GCTs) are rare tumours that can occur in any part of the body but are commonly observed in the skin, digestive tract, and subcutaneous tissues, with the oral cavity being the most common anatomical location. Breast involvement has been reported in a small proportion of cases and is commonly benign. However, some of these lesions can be malignant. In this study, two cases of benign granular breast cell tumours in women aged 31 and 39 years are highlighted and discussed. This study shows similarities between the clinical and radiological presentation of GCTs with breast malignancies and the associated management difficulties that can be encountered.
颗粒细胞瘤（GCTs）是一种罕见肿瘤，可发生于身体的任何部位，但常见于皮肤、消化道和皮下组织，口腔是最常见的解剖部位。有一小部分病例报告了乳腺受累情况，且通常为良性。然而，其中一些病变可能是恶性的。在本研究中，重点介绍并讨论了两例分别为31岁和39岁女性的良性乳腺颗粒细胞瘤病例。本研究显示了颗粒细胞瘤与乳腺恶性肿瘤在临床和影像学表现上的相似性以及可能遇到的相关管理难题。
